一名艾滋病患者在接受氟康唑二级预防后免疫重建，但球孢子菌病仍复发。
Relapse of coccidioidomycosis despite immune reconstitution after fluconazole secondary prophylaxis in a patient with AIDS.
作者信息
Mathew G, Smedema M, Wheat L J, Goldman M
机构信息
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
出版信息
Mycoses. 2003 Feb;46(1-2):42-4. doi: 10.1046/j.1439-0507.2003.00833.x.
Abstract
We report a case of relapse of coccidioidomycosis in an HIV-infected person who discontinued maintenance azole therapy following a response to antiretroviral therapy. This experience raises concern about the safety of withholding secondary prophylaxis for coccidioidomycosis in persons with HIV infection who have achieved immunological responses to antiretroviral therapy.
摘要
我们报告了一例艾滋病病毒感染者球孢子菌病复发的病例，该患者在对抗逆转录病毒治疗产生反应后停用了维持性唑类治疗。这一经历引发了人们对于在对抗逆转录病毒治疗已产生免疫反应的艾滋病病毒感染者中停止球孢子菌病二级预防的安全性的担忧。
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