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一起医院内变形普罗威登斯菌尿路感染暴发。

An outbreak of nosocomial Proteus rettgeri urinary tract infection.

作者信息

Lindsey J O, Martin W T, Sonnenwirth A C, Bennett J V

出版信息

Am J Epidemiol. 1976 Mar;103(3):2461-9.

PMID:1258855
Abstract

Between December 1, 1971, and November 30, 1972, 11 patients on a single physical rehabilitation ward in a large St. Louis, Missouri, community hospital developed Proteus rettgeri urinary tract infections; P. rettgeri isolates from each patient were indole-negative and resistant in vitro to all antibiotics tested. Infected patients were more likely to have indwelling urinary tract catheters than were matched control patients, and all had previously received systemic antibiotic therapy. Retrospective epidemiologic investigation and microbiologic samplig at the time of the investigation failed to detect a common source of infection. Infected patients appeared to be the major reservoir of the epidemic strain, and indirect-contact transmission of the organism via nursing personnel probably occurred. Data collected from a prospective study suggested that placing catheterized patients in rooms that did not contain other catheterized patients may be an effective control measure.

摘要

在1971年12月1日至1972年11月30日期间,密苏里州圣路易斯市一家大型社区医院的一个物理康复病房里,有11名患者发生了雷氏变形杆菌尿路感染;从每名患者身上分离出的雷氏变形杆菌吲哚试验呈阴性,并且在体外对所有测试抗生素均耐药。与匹配的对照患者相比,感染患者更有可能留置导尿管,并且此前均接受过全身抗生素治疗。回顾性流行病学调查以及调查时的微生物采样未能检测到感染的共同来源。感染患者似乎是该流行菌株的主要储存宿主,并且该病原体可能通过护理人员发生了间接接触传播。一项前瞻性研究收集的数据表明,将留置导尿管的患者安置在不包含其他留置导尿管患者的病房中可能是一种有效的控制措施。

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