Aminoff M J, Marshall J, Smith E M, Wyke M A
Psychol Med. 1975 May;5(2):169-72. doi: 10.1017/s0033291700056439.
Cognitive function was evaluated in 11 patients with Huntington's chorea, using eight subtests of the WAIS, and their performance was compared with that previously reported for a normal aged population. The pattern of impairment was similar in the two groups. Tests of immediate memory were given to nine of these patients, and to 10 healthy but aged subjects. In both groups, there was a significant correlation between the performance of individuals in these tests and their IQ, suggesting that the choreic patients had no selective impairment of immediate memory. The clinical and psychological records of the 11 patients revealed no evidence of focal deficits, and the majority of patients were fully orientated and retained insight to their condition. These observations are discussed in relation to the pattern of intellectual impairment seen in other presenile dementias.
使用韦氏成人智力量表的八个分测验对11例亨廷顿舞蹈症患者的认知功能进行了评估，并将他们的表现与先前报道的正常老年人群的表现进行了比较。两组的损伤模式相似。对其中9例患者以及10名健康的老年受试者进行了即时记忆测试。在两组中，个体在这些测试中的表现与他们的智商之间存在显著相关性，这表明舞蹈症患者没有即时记忆的选择性损伤。11例患者的临床和心理记录未显示局灶性缺陷的证据，并且大多数患者定向力完全正常，对自己的病情有自知之明。结合在其他早老性痴呆中所见的智力损伤模式对这些观察结果进行了讨论。
