Horstman D H, Gleser M, Delehunt J
Am J Physiol. 1976 Feb;230(2):327-34. doi: 10.1152/ajplegacy.1976.230.2.327.
Maximal oxygen consumption (VO2 max) and muscle blood flow (Q max) were measured in an isolated gracilis muscle preparation before and after alteration in perfusion pressure (BP), arterial oxygen saturation (SaO2), and hemoglobin concentration (Hb). Q varied directly with BP and inversely with Hb (viscosity) but was unaffected by changes in arterial SaO2. VO2 max varied directly with oxygen delivery under all conditions. These results indicate that VO2 max is normally limited by oxygen delivery rather than any intrinsic limiting of oxygen consumption of the muscle.
在灌注压力（BP）、动脉血氧饱和度（SaO2）和血红蛋白浓度（Hb）改变之前和之后，在分离的股薄肌标本中测量最大耗氧量（VO2 max）和肌肉血流量（Q max）。Q 与 BP 呈正比，与 Hb（粘度）呈反比，但不受动脉 SaO2 变化的影响。在所有条件下，VO2 max 与氧输送呈正比。这些结果表明，VO2 max 通常受氧输送限制，而非肌肉氧消耗的任何内在限制。
