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台湾地区广州管圆线虫所致嗜酸性粒细胞性脑膜炎和脑膜脑炎的临床观察

Clinical observations on eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis on Taiwan.

作者信息

Yii C Y

出版信息

Am J Trop Med Hyg. 1976 Mar;25(2):233-49. doi: 10.4269/ajtmh.1976.25.233.

DOI:10.4269/ajtmh.1976.25.233
PMID:1259085
Abstract

One hundred and twenty-five patients with eosinophilic meningitis or meningoencephalitis were studied in southern Taiwan in 1968 and 1969. The majority of patients had mild to moderate disease, but several had severe manifestations. Four patients died and three others had severe permanent sequelae such as blindness. Young adult Angiostrongylus cantonensis were recovered from nine patients, at autopsy in one, and from the cerebrospinal fluid of eight who survived. The clinical manifestations of cases of proven etiology were similar to those of cases from which parasites were not recovered and it is believed that the latter also were the result of infection with A. cantonensis.

摘要

1968年至1969年,对台湾南部125例嗜酸性粒细胞性脑膜炎或脑膜脑炎患者进行了研究。大多数患者患有轻至中度疾病,但有几例出现严重症状。4例患者死亡,另外3例有严重的永久性后遗症,如失明。在9例患者中发现了广州管圆线虫成虫,1例在尸检时发现,8例存活患者的脑脊液中也发现了该寄生虫。病因已明确的病例的临床表现与未发现寄生虫的病例相似,据信后者也是广州管圆线虫感染的结果。

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