Fries Pascal, Fernández Guillén, Jensen Ole
F.C. Donders Centre for Cognitive Neuroimaging, Adelbertusplein 1, 6525 EK Nijmegen, The Netherlands.
Trends Neurosci. 2003 Mar;26(3):123-4. doi: 10.1016/S0166-2236(03)00023-7.
Although long-term memory is central among our cognitive functions, the search for a direct neurophysiological correlate to it has proven difficult. The formation of new memories depends on the hippocampus and adjacent cortex, but the final storage is thought to be in a widely distributed neocortical network. Recent experiments, using simultaneous recordings from hundreds of sites in monkey neocortex, have revealed the activation of such a distributed network -- probably reflecting the consolidation of long-term memory storage.
尽管长期记忆在我们的认知功能中处于核心地位,但寻找与之直接相关的神经生理关联物却颇具难度。新记忆的形成依赖于海马体及相邻皮质,但最终存储被认为是在广泛分布的新皮质网络中。最近,通过对猴子新皮质数百个位点进行同步记录的实验,揭示了这样一个分布式网络的激活——这可能反映了长期记忆存储的巩固过程。