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[幽门螺杆菌感染的血清学诊断]

[Serodiagnosis of Helicobacter pylori infection].

作者信息

Presecki Vladimir, Katicić Miroslava, Marusić Marinko, Kalenić Smilja, Strnad Marija, Plecko Vanda, Babus Vladimir, Dominis Mara

机构信息

Zavod za mikrobiologiju i paraznologiju SNZ A. Stampar Medicinskog fakulteta Sveucilista u Zagrebu, Rockefellerova 4, 10000 Zagreb.

出版信息

Lijec Vjesn. 2002 Sep;124 Suppl 1:23-8.

Abstract

Infection with Helicobacter pylori induces antibodies, but these are not able to eradicate the bacterium from the gastric mucosa. Enzyme linked immunosorbent assay is the laboratory based method and most commonly used to measure qualitatively and quantitatively anti-Helicobacter pylori antibodies of different immunoglobulin classes in almost all infected patients. Quantitative serological tests are useful in the follow-up of eradication therapy. Serology is the method of choice in population studies and in the retrospective analysis of stored serum samples to study the natural course of this chronic infection.

摘要

幽门螺杆菌感染会诱导产生抗体,但这些抗体无法从胃黏膜中清除该细菌。酶联免疫吸附测定是一种基于实验室的方法,最常用于几乎所有感染患者中定性和定量检测不同免疫球蛋白类别的抗幽门螺杆菌抗体。定量血清学检测在根除治疗的随访中很有用。血清学是人群研究以及对储存血清样本进行回顾性分析以研究这种慢性感染自然病程时的首选方法。

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