一种海洋交替单胞菌产生的大分子聚阴离子抗生素对细菌呼吸作用的修饰
Modification of bacterial respiration by a macromolecular polyanionic antibiotic produced by a marine Alteromonas.
作者信息
Gauthier M J
出版信息
Antimicrob Agents Chemother. 1976 Mar;9(3):361-6. doi: 10.1128/AAC.9.3.361.
Abstract
A macromolecular polyanionic antibiotic produced by a marine bacterium belonging to the genus Alteromonas causes a large modification in bacterial respiration when added to the culture of several bacterial species in their early stage of growth. This antibiotic induces an increase of oxygen uptake and the production of hydrogen peroxide. The latter fact explains the high sensitivity of bacteria with low catalase activity and the antagonistic effect of pure catalase on antibiosis. The antibiotic could act at the level of the respiratory chain by setting up a flavinic respiration.
摘要
一种由交替单胞菌属海洋细菌产生的大分子聚阴离子抗生素，在添加到几种细菌物种生长早期的培养物中时，会引起细菌呼吸的巨大变化。这种抗生素会诱导氧气摄取增加和过氧化氢的产生。后一事实解释了过氧化氢酶活性低的细菌的高敏感性以及纯过氧化氢酶对抗生素作用的拮抗效应。该抗生素可能通过建立黄素呼吸作用在呼吸链水平发挥作用。
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本文引用的文献
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