Edwards A E, Shellow W V, Wright E T, Dignam T F
Arch Dermatol. 1976 Mar;112(3):339-43.
A method of inducing controlled levels of terminable itching was developed. This method consists of administering constant monophasic pulsations of electric current by means of noninvasive electrodes. Once experimental pruritus had been reliably reproduced, two variables, hypothesized to be relevant to the perception of itching, were investigated, viz, the presence of a positive or a negative history of a pruritic dermatosis, and the presence of a high or low level of psychological stress. Both variables were found to be related to the perception of itching, but in different manners. A positive history of a pruritic dermatosis lowered the threshold for the perception of itch stimuli, while a high level of psychological stress enhanced the ability to discriminate among the more intense itch stimuli, with no effect on the itch threshold.
开发了一种诱导可控程度的可终止瘙痒的方法。该方法包括通过无创电极施加恒定的单相电流脉冲。一旦可靠地再现了实验性瘙痒，就对两个被假设与瘙痒感知相关的变量进行了研究，即瘙痒性皮肤病的阳性或阴性病史的存在，以及高或低水平心理压力的存在。发现这两个变量都与瘙痒感知有关，但方式不同。瘙痒性皮肤病的阳性病史降低了瘙痒刺激感知的阈值，而高水平的心理压力增强了区分更强烈瘙痒刺激的能力，对瘙痒阈值没有影响。
