Scott O, Macartney F J, Deverall P B
Arch Dis Child. 1976 Feb;51(2):100-5. doi: 10.1136/adc.51.2.100.
The ages of 6 male patients with the sick sinus syndrome ranged from 10-15 years when their symptoms began. At rest all had a heart rate of 60/min or less. Two had syncopal attacks which threatened life; 1 had only attacks of dizziness; the other 3 had no syncopal attacks but had recurrent attacks of supraventricular tachycardia ('brady-tachycardia syndrome') which were more resistant to drug therapy than is usual in childhood. They were not controlled or suppressed by digoxin when it was given. Substernal pain occurred in 2 patients who had syncope. In all patients the heart rate remained inappropriately slow after exercise and atropine. Cardiac pacemakers were used in the 2 patients with life-threatening syncope. Any patient who has dizziness or syncopal attacks and an inappropriately slow heart rate should have electrocardiograms recorded at rest and after exercise to record the heart rate and to look for abnormal P-waves.
6例患病态窦房结综合征的男性患者症状开始出现时年龄在10至15岁之间。静息时所有人的心率均为每分钟60次或更低。2人有危及生命的晕厥发作；1人仅有头晕发作；另外3人无晕厥发作，但有室上性心动过速反复发作（“慢-快综合征”），且对药物治疗的抵抗性比儿童期通常情况更强。给予地高辛时，这些发作未得到控制或抑制。2例有晕厥的患者出现胸骨后疼痛。在所有患者中，运动和使用阿托品后心率仍异常缓慢。2例有危及生命的晕厥的患者使用了心脏起搏器。任何有头晕或晕厥发作且心率异常缓慢的患者都应在静息和运动后记录心电图，以记录心率并寻找异常P波。
