Mackintosh A F
Br Heart J. 1981 Jan;45(1):62-6. doi: 10.1136/hrt.45.1.62.
A survey at three cardiac centres disclosed nine patients under the age of 25 years with sinus node dysfunction in the absence of other forms of heart disease. All were male and seven were above the 90th centile for height. Ambulatory monitoring was performed on all the first-degree relatives of six of the patients and three families showed conducting system disturbances in the form of sinuatrial disorders or delayed atrioventricular conduction. A genetic factor may be involved in the aetiology of sinuatrial disease in young people.
对三个心脏中心的一项调查发现,有9名25岁以下的患者存在窦房结功能障碍,且无其他形式的心脏病。所有患者均为男性,其中7人的身高高于第90百分位数。对6名患者的所有一级亲属进行了动态监测,有3个家庭出现了以窦房结疾病或房室传导延迟形式的传导系统紊乱。遗传因素可能与年轻人窦房结疾病的病因有关。