Omachi Naoki, Ishikawa Hideo, Hara Masahiko, Nishihara Takashi, Yamaguchi Yu, Yamamoto Yumiko, Youmoto Mihoko, Hattori Tomoaki, Kitaguchi Kazushi, Yamamoto Shota, Kawaguchi Tomoya, Fukuzawa Masahiro
Hemoptysis and Pulmonary-Circulation Center, Eishinkai Kishiwada Rehabilitation Hospital, Kamimatsu-Chou 2-8-10, Kishiwada, Osaka, 596-0827, Japan.
Center for Community-Based Healthcare Research and Education, Shimane University Graduate School of Medicine, Izumo, Japan.
Eur Radiol. 2021 Jul;31(7):5351-5360. doi: 10.1007/s00330-020-07533-x. Epub 2021 Jan 6.
Patients with haemoptysis often experience daily physical and mental impairment. Bronchial artery embolisation is among the first-line treatment options used worldwide; however, no evidence exists regarding the health-related quality of life (HRQoL) after bronchial artery embolisation. Therefore, this study aimed to evaluate the effects of bronchial artery embolisation on the HRQoL of patients with haemoptysis.
We prospectively enrolled 61 consecutive patients who visited our hospital from July 2017 to August 2018 and received bronchial artery embolisation for haemoptysis. The primary outcome was the HRQoL evaluated using the Short Form Health Survey, which contains physical and mental components, before and after bronchial artery embolisation. The secondary outcomes were procedural success, complications, and recurrence-free survival rate at 6 months.
The mean age of the patients was 69 years (range, 31-87 years). The procedural success rate was 98%. No major complications occurred. The recurrence-free survival rate estimated using the Kaplan-Meier analysis at 6 months after bronchial artery embolisation was 91.8% (95% confidence interval, 91.1-92.5%). Compared with the pre-treatment scores, the physical and mental scores were significantly improved at 6 months after bronchial artery embolisation (p < 0.05).
Bronchial artery embolisation improved the HRQoL of patients with haemoptysis.
• Bronchial artery embolisation improved the HRQoL of patients with haemoptysis. • Vessel dilation on computed tomography and systemic artery-pulmonary artery direct shunting on angiography were the most common abnormalities. • The recurrence-free survival rate estimated using the Kaplan-Meier analysis at 6 months after bronchial artery embolisation was 91.8%.
咯血患者常每日遭受身心损害。支气管动脉栓塞术是全球范围内使用的一线治疗选择之一;然而,关于支气管动脉栓塞术后与健康相关的生活质量(HRQoL)尚无证据。因此,本研究旨在评估支气管动脉栓塞术对咯血患者HRQoL的影响。
我们前瞻性纳入了2017年7月至2018年8月期间连续就诊于我院并因咯血接受支气管动脉栓塞术的61例患者。主要结局是使用包含身体和心理成分的简短健康调查问卷在支气管动脉栓塞术前和术后评估的HRQoL。次要结局是手术成功率、并发症以及6个月时的无复发生存率。
患者的平均年龄为69岁(范围31 - 87岁)。手术成功率为98%。未发生重大并发症。支气管动脉栓塞术后6个月使用Kaplan - Meier分析估计的无复发生存率为91.8%(95%置信区间,91.1 - 92.5%)。与治疗前评分相比,支气管动脉栓塞术后6个月时身体和心理评分显著改善(p < 0.05)。
支气管动脉栓塞术改善了咯血患者的HRQoL。
• 支气管动脉栓塞术改善了咯血患者的HRQoL。• 计算机断层扫描上的血管扩张和血管造影上的体动脉 - 肺动脉直接分流是最常见的异常情况。• 支气管动脉栓塞术后6个月使用Kaplan - Meier分析估计的无复发生存率为91.8%。