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小肠旁路手术治疗重度肥胖对胃分泌功能影响的研究。

Studies on the effect of small bowel bypass for massive obesity on gastric secretory function.

作者信息

Wise L, Vaughan R, Stein T

出版信息

Ann Surg. 1976 Mar;183(3):259-62. doi: 10.1097/00000658-197603000-00007.

DOI:10.1097/00000658-197603000-00007
PMID:1259481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1344233/
Abstract

Gastric secretory function was studied in 20 morbidly obese patients both before and after jejuno-ileal bypass. The mean postoperative weight loss was 99.2 pounds during a mean postoperative followup period of 12.6 months. The gastric secretory values we studied included basal and histalogstimulated volume, pH, concentration, and output. No statistically significant changes were observed in any of these variables. Therefore it is suggested that jejuno-ileal bypass, as performed for morbid obesity, is probably not an ulcerogenic procedure.

摘要

对20例病态肥胖患者在空肠回肠旁路手术前后的胃分泌功能进行了研究。术后平均随访12.6个月期间,平均体重减轻了99.2磅。我们研究的胃分泌值包括基础值和组胺刺激后的容量、pH值、浓度及分泌量。这些变量均未观察到有统计学意义的变化。因此,对于病态肥胖患者施行的空肠回肠旁路手术可能不是一种致溃疡的手术。

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1
Studies on the effect of small bowel bypass for massive obesity on gastric secretory function.小肠旁路手术治疗重度肥胖对胃分泌功能影响的研究。
Ann Surg. 1976 Mar;183(3):259-62. doi: 10.1097/00000658-197603000-00007.
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Gastric hypersecretion after formation of small bowel conduits: a common factor in several clinical states.小肠导管形成后的胃酸分泌过多:多种临床状态的一个共同因素。
Ann Surg. 1979 Mar;189(3):313-6. doi: 10.1097/00000658-197903000-00011.
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Hyperacidity and hypergastrinemia following extensive intestinal resection.广泛肠切除术后的胃酸过多和高胃泌素血症
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本文引用的文献

1
MECHANISM OF DUODENAL INHIBITION OF GASTRIC SECRETION.十二指肠抑制胃酸分泌的机制。
Arch Surg. 1964 Oct;89:585-91. doi: 10.1001/archsurg.1964.01320040001001.
2
Mechanism of gastric hypersecretion following massive intestinal resection. Clinical and experimental observations.大肠大部切除术后胃酸分泌过多的机制。临床及实验观察
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Changes in gastric acid secretion following resection or exclusion of different segments of the small intestine.小肠不同节段切除或旷置后胃酸分泌的变化
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Effect of small-bowel bypass on gastric secretion in obese patients.小肠旁路手术对肥胖患者胃分泌的影响。
Can J Surg. 1968 Jul;11(3):365-8.
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The effect of small bowel resection on gastric acid secretion in the rat.
Surgery. 1969 Feb;65(2):292-7.
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Effect of small bowel bypass on gastric secretory function: postintestinal exclusion hypersecretion, a phenomenon in search of a syndrome.小肠旁路手术对胃分泌功能的影响:肠排除术后分泌过多,一种有待明确综合征的现象。
Surgery. 1974 Jun;75(6):821-8.
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Peptic ulcer: a reappraisal of its aetiology.消化性溃疡:对其病因学的重新评估。
Ann R Coll Surg Engl. 1972 Mar;50(3):145-63.
8
The influence of resection of the small intestine on gastrin levels.
Surg Gynecol Obstet. 1975 Jan;140(1):27-9.