Forrest J F, Longmire W P
Ann Surg. 1979 Mar;189(3):313-6. doi: 10.1097/00000658-197903000-00011.
As a preliminary step in studying the effect on gastric acid secretion in dogs following biliary diversion through isolated intestinal conduits, blind-ended intestinal conduits were constructed and the biliary channel was left undisturbed at this time. The results were surprising in that a significant absolute increase in gastric acid secretion occurred in all dogs, within the range of 65-286%, by merely disconnecting a segment of small bowel from the mainstream of flow of intestinal contents. This effect may be due to the "intestinal phase of gastric secretion hormone" and may in itself provide a partial explanation for the well-documented increase in gastric acid production caused by the Exalto-Mann-Williamson procedure and by choledochoenterostomy utilizing a Roux loop.
作为研究通过孤立肠管进行胆汁分流对犬胃酸分泌影响的初步步骤，构建了盲端肠管，此时胆管通道未受干扰。结果令人惊讶，仅通过将一段小肠与肠内容物流主流断开，所有犬的胃酸分泌均出现了显著的绝对增加，增幅在65% - 286%之间。这种效应可能归因于“胃分泌激素的肠期”，并且其本身可能为Exalto - Mann - Williamson手术以及利用Roux袢的胆总管空肠吻合术所导致的胃酸分泌增加提供部分解释，这一现象已有充分记录。
