急性韦尼克脑病的磁共振扩散加权成像

Diffusion weighted MR imaging of acute Wernicke's encephalopathy.

作者信息

Chung Tae-Ick, Kim Joong-Seok, Park Soung-Kyeong, Kim Beum-Saeng, Ahn Kook-Jin, Yang Dong-Won

机构信息

Department of Neurology, College of Medicine, The Catholic University of Korea, Youido St Mary's Hospital, #62 Youido-dong, Youngdungpo-gu, Seoul 150-071, South Korea.

出版信息

Eur J Radiol. 2003 Mar;45(3):256-8. doi: 10.1016/s0720-048x(02)00009-8.

DOI:10.1016/s0720-048x(02)00009-8

PMID:12595110

Abstract

We report a case of Wernicke's encephalopathy in which diffusion-weighted MR images demonstrated symmetrical hyperintense lesions in the paraventricular area of the third ventricles and medial thalami. Apparent diffusion coefficient mapping showed isointensity in the aforementioned areas. Diffusion-weighted MR images may provide evidence of vasogenic edema associated with thiamine deficiency, proven in the histopathology of experimental animals. In addition, diffusion-weighted MRI has many advantages over T2 or FLARE-weighted brain MRI in detecting structural and functional abnormalities in Wernicke's encephalopathy.

摘要

我们报告一例韦尼克脑病，其磁共振扩散加权成像显示第三脑室室旁区域及内侧丘脑有对称性高信号病变。表观扩散系数图显示上述区域等信号。磁共振扩散加权成像可能提供与硫胺素缺乏相关的血管源性水肿的证据，这在实验动物的组织病理学中得到证实。此外，在检测韦尼克脑病的结构和功能异常方面，磁共振扩散加权成像比T2加权或液体衰减反转恢复序列加权脑磁共振成像具有许多优势。