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[韦尼克脑病：妊娠剧吐的一种罕见并发症]

[Wernicke's encephalopathy: a rare complication of hyperemesis gravidarum].

作者信息

Nasri Soumaya, Aichouni Narjisse, Ettayeb Mounia, Mebrouk Yassine, Kamaoui Imane

机构信息

Service de Radiologie et d'Imagerie Médicale, CHU Mohammed VI, Oujda, Maroc.

Service de Neurologie, CHU Mohammed VI, Oujda, Maroc.

出版信息

Pan Afr Med J. 2020 Aug 11;36:267. doi: 10.11604/pamj.2020.36.267.18468. eCollection 2020.

DOI:10.11604/pamj.2020.36.267.18468
PMID:33088396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7545981/
Abstract

Wernicke's encephalopathy is a deficiency disease resulting from severe thiamine deficiency (vitamin B1). It mainly occurs in alcoholic subjects, but sometimes it is difficult to diagnose. The absence of treatment leads to severe cognitive sequelae. Magnetic resonance imaging is the gold standard imaging modality to confirm the diagnosis. The diagnostic sign is T2-weighted hyperintensity in the periaqueducal, thalami and mammillary bodies. We report the case of a 30-year-old woman with abundant vomiting during the first trimester of pregnancy (hyperemesis gravidarum), causing symptomatic Wernicke's encephalopathy.

摘要

韦尼克脑病是一种由于严重硫胺素缺乏（维生素B1）导致的营养缺乏病。它主要发生在酗酒者中，但有时难以诊断。若不进行治疗会导致严重的认知后遗症。磁共振成像（MRI）是确诊该病的金标准影像学检查方法。诊断征象为导水管周围、丘脑和乳头体在T2加权像上呈高信号。我们报告了一例30岁女性的病例，该患者在妊娠早期出现频繁呕吐（妊娠剧吐），进而引发了症状性韦尼克脑病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/629a800b8d6a/PAMJ-36-267-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/23e6560a6c57/PAMJ-36-267-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/59170f710cae/PAMJ-36-267-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/6fdec3605445/PAMJ-36-267-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/629a800b8d6a/PAMJ-36-267-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/23e6560a6c57/PAMJ-36-267-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/59170f710cae/PAMJ-36-267-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/6fdec3605445/PAMJ-36-267-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/629a800b8d6a/PAMJ-36-267-g004.jpg

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Seizures in the third trimester of pregnancy- A rare case of Wernicke's encephalopathy mimicking Eclampsia.妊娠晚期癫痫发作——一例罕见的酷似子痫的韦尼克脑病病例。
Radiol Case Rep. 2024 Mar 1;19(5):2039-2042. doi: 10.1016/j.radcr.2024.02.031. eCollection 2024 May.
2
Uncommon bilateral optic neuropathy in Wernicke's encephalopathy complicating gravidarum hyperemesis.妊娠剧吐并发韦尼克脑病导致不常见的双侧视神经病变。
Tunis Med. 2023 May 5;101(5):530-532.
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Wernicke Syndrome: Case Report and Literature Review of Contributing Factors-Can Malpractice Dynamics Be Identified?

本文引用的文献

1
[Hypokaliemic myopathy: a rare complication of hyperemesis gravidarum].[低钾血症性肌病：妊娠剧吐的一种罕见并发症]
Ann Fr Anesth Reanim. 2009 Jul-Aug;28(7-8):713. doi: 10.1016/j.annfar.2009.05.008. Epub 2009 Jul 3.
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MR imaging findings in 56 patients with Wernicke encephalopathy: nonalcoholics may differ from alcoholics.56例韦尼克脑病患者的磁共振成像表现：非酒精性患者可能与酒精性患者有所不同。
AJNR Am J Neuroradiol. 2009 Jan;30(1):171-6. doi: 10.3174/ajnr.A1280. Epub 2008 Oct 22.
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Clinical characteristics and MR imaging features of nonalcoholic Wernicke encephalopathy.
韦尼克脑病：病例报告及促成因素的文献综述——能否识别医疗过失动态？
J Clin Med. 2024 Jan 26;13(3):716. doi: 10.3390/jcm13030716.
非酒精性韦尼克脑病的临床特征及磁共振成像特征
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[Hyperemesis gravidarum: a rare cause of Wernicke encephalopathy].[妊娠剧吐：韦尼克脑病的罕见病因]
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[Brain MR imaging of chronic alcoholism].[慢性酒精中毒的脑部磁共振成像]
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Hyperemesis gravidarum complicated by Wernicke's encephalopathy.妊娠剧吐合并韦尼克脑病
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Wernicke encephalopathy in nonalcoholic patients.非酒精性患者的韦尼克脑病
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9
Diffusion-weighted imaging abnormalities in wernicke encephalopathy: reversible cytotoxic edema?韦尼克脑病中的弥散加权成像异常：可逆性细胞毒性水肿？
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Wernicke's encephalopathy due to hyperemesis gravidarum: an under-recognised condition.妊娠剧吐所致韦尼克脑病：一种未被充分认识的病症。
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