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[韦尼克脑病:妊娠剧吐的一种罕见并发症]

[Wernicke's encephalopathy: a rare complication of hyperemesis gravidarum].

作者信息

Nasri Soumaya, Aichouni Narjisse, Ettayeb Mounia, Mebrouk Yassine, Kamaoui Imane

机构信息

Service de Radiologie et d'Imagerie Médicale, CHU Mohammed VI, Oujda, Maroc.

Service de Neurologie, CHU Mohammed VI, Oujda, Maroc.

出版信息

Pan Afr Med J. 2020 Aug 11;36:267. doi: 10.11604/pamj.2020.36.267.18468. eCollection 2020.

Abstract

Wernicke's encephalopathy is a deficiency disease resulting from severe thiamine deficiency (vitamin B1). It mainly occurs in alcoholic subjects, but sometimes it is difficult to diagnose. The absence of treatment leads to severe cognitive sequelae. Magnetic resonance imaging is the gold standard imaging modality to confirm the diagnosis. The diagnostic sign is T2-weighted hyperintensity in the periaqueducal, thalami and mammillary bodies. We report the case of a 30-year-old woman with abundant vomiting during the first trimester of pregnancy (hyperemesis gravidarum), causing symptomatic Wernicke's encephalopathy.

摘要

韦尼克脑病是一种由于严重硫胺素缺乏(维生素B1)导致的营养缺乏病。它主要发生在酗酒者中,但有时难以诊断。若不进行治疗会导致严重的认知后遗症。磁共振成像(MRI)是确诊该病的金标准影像学检查方法。诊断征象为导水管周围、丘脑和乳头体在T2加权像上呈高信号。我们报告了一例30岁女性的病例,该患者在妊娠早期出现频繁呕吐(妊娠剧吐),进而引发了症状性韦尼克脑病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2976/7545981/23e6560a6c57/PAMJ-36-267-g001.jpg

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