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双硫仑与美沙酮联合使用的医疗安全性。酒精成瘾性海洛因成瘾者的药物治疗。

The medical safety of the combined usage of disulfiram and methadone. Pharmacological treatment for alcoholic heroin addicts.

作者信息

Charuvastra C V, Panell J, Hopper M, Erhmann M, Blakis M, Ling W

出版信息

Arch Gen Psychiatry. 1976 Mar;33(3):391-3. doi: 10.1001/archpsyc.1976.01770030085013.

DOI:10.1001/archpsyc.1976.01770030085013
PMID:1259527
Abstract

The results of hematology and blood chemistry tests were examined in eight methadone maintenance patients who had been treated concurrently for alcoholism with disulfiram (Antabuse). There were no apparent major differences between the results of tests run prior to the initiation of the disulfiram treatment and subsequent tests run up to 16 months after treatment was begun. There was a trend toward normalization of serum glutamic oxaloacetic transaminase (SGOT) values. The results suggested no contraindications to this combined pharmacological treatment.

摘要

对八名美沙酮维持治疗患者的血液学和血液化学测试结果进行了检查,这些患者同时接受了双硫仑(戒酒硫)治疗酒精成瘾。在开始双硫仑治疗之前进行的测试结果与治疗开始后长达16个月的后续测试结果之间没有明显的主要差异。血清谷草转氨酶(SGOT)值有趋于正常的趋势。结果表明这种联合药物治疗没有禁忌证。

相似文献

1
The medical safety of the combined usage of disulfiram and methadone. Pharmacological treatment for alcoholic heroin addicts.双硫仑与美沙酮联合使用的医疗安全性。酒精成瘾性海洛因成瘾者的药物治疗。
Arch Gen Psychiatry. 1976 Mar;33(3):391-3. doi: 10.1001/archpsyc.1976.01770030085013.
2
Combined behavioral and pharmacological treatment of alcoholic methadone patients.
J Subst Abuse. 1988;1(2):161-71. doi: 10.1016/s0899-3289(88)80019-1.
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A behavioral treatment of alcoholic methadone patients.对酒精成瘾美沙酮患者的行为治疗。
Ann Intern Med. 1978 Sep;89(3):342-4. doi: 10.7326/0003-4819-89-3-342.
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The treatment of alcoholic methadone patients: a review.酒精成瘾美沙酮患者的治疗:综述
J Subst Abuse Treat. 1987;4(1):15-9. doi: 10.1016/0740-5472(87)90005-5.
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Use of disulfiram for alcoholics in methadone maintenance programs. A Veterans Administration Cooperative Study.在美沙酮维持治疗项目中使用双硫仑治疗酗酒者。一项退伍军人管理局合作研究。
Arch Gen Psychiatry. 1983 Aug;40(8):851-4. doi: 10.1001/archpsyc.1983.01790070041005.
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Disulfiram (Antabuse) in the treatment of methadone maintenance alcoholics.双硫仑(戒酒硫)用于美沙酮维持治疗的酗酒者。
Proc Natl Conf Methadone Treat. 1973;1:316-23.
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Treatment of alcoholic methadone-maintenance patients with disulfiram.用双硫仑治疗酒精成瘾的美沙酮维持治疗患者。
J Stud Alcohol. 1975 Nov;36(11):1584-8. doi: 10.15288/jsa.1975.36.1584.
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Alcohol-abusing methadone patients.滥用酒精的美沙酮患者。
Alcohol Clin Exp Res. 1994 Jun;18(3):767-8. doi: 10.1111/j.1530-0277.1994.tb00945.x.
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A behavioural-pharmacological treatment of dually addicted patients.对双重成瘾患者的行为药理学治疗。
Behav Res Ther. 1972 Nov;10(4):403-5. doi: 10.1016/0005-7967(72)90064-2.
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Alcoholism among methadone patients: a specific treatment method.美沙酮患者中的酗酒问题:一种特定的治疗方法。
Am J Psychiatry. 1973 Apr;130(4):483-5. doi: 10.1176/ajp.130.4.483.

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Effects of disulfiram on QTc interval in non-opioid-dependent and methadone-treated cocaine-dependent patients.双硫仑对非阿片类依赖和接受美沙酮治疗的可卡因依赖患者 QTc 间期的影响。
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