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酒精成瘾美沙酮患者的治疗:综述

The treatment of alcoholic methadone patients: a review.

作者信息

Bickel W K, Marion I, Lowinson J H

出版信息

J Subst Abuse Treat. 1987;4(1):15-9. doi: 10.1016/0740-5472(87)90005-5.

DOI:10.1016/0740-5472(87)90005-5
PMID:3302285
Abstract

Alcoholism is a major problem among methadone maintenance patients. Although alcoholism in the methadone patient is recognized as a problem, few treatment studies have been conducted. Treatment studies have examined abstinence oriented and controlled drinking therapies, voluntary disulfiram treatment, and combined behavioral-pharmacological treatment. The first three treatments were shown to be ineffective in impacting alcohol consumption. The ineffectiveness reported by these studies was attributed to patients' lack of motivation. However, the combined behavioral-pharmacological treatment, which made methadone treatment contingent on antabuse consumption, resulted in decreases in both alcohol consumption and arrests, with increases occurring in employment. Future research should examine the generality of the findings from combined treatment as well as examine whether other contingency management procedures may reduce alcohol consumption in the alcoholic methadone patient.

摘要

酗酒是美沙酮维持治疗患者中的一个主要问题。尽管美沙酮患者的酗酒问题已得到认可,但相关治疗研究却很少。治疗研究考察了戒酒导向和控制性饮酒疗法、自愿服用双硫仑治疗以及行为-药物联合治疗。结果显示,前三种治疗方法在减少酒精摄入量方面无效。这些研究报告的无效性归因于患者缺乏动机。然而,行为-药物联合治疗使美沙酮治疗取决于安塔布司(双硫仑)的服用,这使得酒精摄入量和被捕次数减少,就业人数增加。未来的研究应检验联合治疗结果的普遍性,以及考察其他应急管理程序是否可以减少酗酒美沙酮患者的酒精摄入量。

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The treatment of alcoholic methadone patients: a review.酒精成瘾美沙酮患者的治疗:综述
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