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[精神分裂症精神病患者治疗中阳性症状的心理治疗]

[Psychotherapy of positive symptoms in the treatment of patients with schizophrenia psychosis].

作者信息

Wiedemann G, Klingberg S

机构信息

Universitätsklinik für Psychiatrie und Psychotherapie Tübingen.

出版信息

Nervenarzt. 2003 Jan;74(1):76-84. doi: 10.1007/s00115-002-1330-3.

Abstract

While the treatment of positive symptoms of patients with schizophrenic psychosis appeared until recently to be solely pharmacotherapeutic, new research findings show the efficacy of cognitive-behavioural psychotherapy (CBT) on positive symptoms in chronic psychotic patients. In addition, the effectiveness even in acute and recent-onset psychosis could be shown in some studies. The effects of CBT and standard care in psychosis compared to standard care alone and to other psychosocial interventions plus standard care are reviewed. The results of several studies and one meta-analysis show that CBT in schizophrenia patients has a direct effect on psychotic symptoms such as hallucinations as well as on relapse prevention. In routine settings,however,CBT has until now only rarely been delivered to these patients. In so-called large pragmatic trials, which might be subsumed as phase IIIb studies, the effects are tested. The therapeutic approach with the components of CBT for psychosis are described: building a therapeutic relationship, cognitive-behavioural coping strategies, developing an understanding of the experience of psychosis,working on hallucinations and delusions, addressing negative self-evaluations, anxiety, and depression,managing risk of relapse and social disability. Further clinical implications are described (capability of learning the therapeutic strategies, deliverability in broader clinical settings, acceptability by patients, combination with atypical neuroleptic drugs,and treatment of choice in risk populations).

摘要

虽然直到最近,精神分裂症性精神病患者阳性症状的治疗似乎还完全是药物治疗,但新的研究结果表明,认知行为心理治疗(CBT)对慢性精神病患者的阳性症状有效。此外,一些研究表明,CBT甚至对急性和近期发病的精神病也有效果。本文综述了CBT和标准护理在精神病治疗中的效果,并与单独的标准护理以及其他心理社会干预加标准护理进行了比较。多项研究和一项荟萃分析的结果表明,CBT对精神分裂症患者的幻觉等精神病症状以及预防复发有直接作用。然而,在常规环境中,到目前为止,这些患者很少接受CBT治疗。在所谓的大型实用性试验(可归类为IIIb期研究)中,对其效果进行了测试。本文描述了针对精神病的CBT组成部分的治疗方法:建立治疗关系、认知行为应对策略、培养对精神病体验的理解、处理幻觉和妄想、解决消极的自我评价、焦虑和抑郁、管理复发风险和社会残疾。还描述了进一步的临床意义(学习治疗策略的能力、在更广泛临床环境中的可实施性、患者的可接受性、与非典型抗精神病药物的联合使用以及高危人群的首选治疗方法)。

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