Arevalo R P, Bullabh P, Krauss A N, Auld P A M, Spigland Nitsana
New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA.
J Pediatr Surg. 2003 Feb;38(2):251-3. doi: 10.1053/jpsu.2003.50056.
The authors report 2 cases of premature neonates who had enterocutaneous fistula complicating necrotizing enterocolitis. Pulmonary hypertension developed after administration of a somatostatin analogue, octreotide, to enhance resolution of the fistula. The authors discuss the mechanism of the occurrence of this complication and recommend caution of its use in high-risk premature neonates.
作者报告了2例患有坏死性小肠结肠炎并发肠皮肤瘘的早产儿。在使用生长抑素类似物奥曲肽以促进瘘管愈合后出现了肺动脉高压。作者讨论了这种并发症发生的机制，并建议在高危早产儿中谨慎使用该药。
