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中枢神经系统囊尾蚴病中的脑脊液免疫球蛋白

Cerebrospinal fluid immunoglobulins in cysticercosis of the central nervous system.

作者信息

Spina-França A, Livramento J A, Bacheschi L A, Garcia-Lopes P

出版信息

Arq Neuropsiquiatr. 1976 Mar;34(1):40-5. doi: 10.1590/s0004-282x1976000100004.

Abstract

Investigation on the behavior of immunoglobulins IGG, IGA and IGM in the CSF in cases of cysticercosis of the CNS, based on data pertaining to two different series of cases. The first series comprises 30 samples of CSF, and the second one, 5 samples. It was demonstrated that IGG is the one representing the largest contingent. IGG concentration keeps in proportion with the gamma globulin concentration, of which it represented an 88% average in the cases studied. Participation of IGG in the protein profile of the CSF is greater than the usually referred; the results for the material analyzed showed 16%. It was verified a proporcionality also between IGG concentration and the titer of positive complement fixation test for cysticercosis; there is a positive correlation, whose numerical expression was found to be significant in the samples studied.

摘要

基于两个不同系列病例的数据,对中枢神经系统囊尾蚴病患者脑脊液中免疫球蛋白IgG、IgA和IgM的行为进行研究。第一个系列包括30份脑脊液样本,第二个系列包括5份样本。结果表明,IgG是占比最大的一种。IgG浓度与γ球蛋白浓度成比例,在所研究的病例中,IgG平均占γ球蛋白的88%。IgG在脑脊液蛋白质谱中的参与度高于通常提及的情况;分析材料的结果显示为16%。还证实了IgG浓度与囊尾蚴病补体结合试验阳性滴度之间也存在比例关系;存在正相关,在所研究的样本中发现其数值表达具有显著性。

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