Monteiro E, Varzim G, Lopes C, Ferreira E
ORL Department, Portuguese Institute of Oncology, Porto, Portugal.
An Otorrinolaringol Ibero Am. 2002;29(6):559-71.
Laryngeal cancer is relatively frequent in South Europe countries and its incidence suffered variations in last decades. Treatment options are usually based on histology, T category and stage. Tumors unchain in neighbour tissues the presence of cells that normally are associated to inflammatory response. A possible association between tumour inflammatory response and radiotherapy efficacy is focused in occasional papers. Several histological parameters (histologic type, nuclear grade, desmoplasia, necrosis, and cells normally involved in inflammatory response) were analysed in biopsy material obtained from 67 patients with laryngeal cancer treated with primary radiotherapy in our department. Statistical analyses were made in order to assess a possible association between tumour morphology and radiotherapy response.
喉癌在南欧国家相对常见，其发病率在过去几十年有所变化。治疗方案通常基于组织学、T分类和分期。肿瘤在邻近组织中引发通常与炎症反应相关的细胞的出现。肿瘤炎症反应与放射治疗疗效之间的可能关联在一些偶尔发表的论文中有所探讨。我们科室对67例接受原发性放射治疗的喉癌患者的活检材料进行了分析，分析了几个组织学参数（组织学类型、核分级、纤维组织增生、坏死以及通常参与炎症反应的细胞）。进行了统计分析以评估肿瘤形态与放射治疗反应之间的可能关联。
