[The effect of unithiol on the changes in immunotoxicity of 2-chloroethenylchloroarsine].

The results of experiments on Wistar rats under conditions of acute intoxication with 2-chloroethenyldichloroarsine (beta-chlorovinyldichloroarsine) (0.75 LD50) showed that unithiol increases antiinfectious nonspecific resistance (NSR) of the organism. This is manifested by improved NSR characteristics: increased activity of the natural killer cells, predominant formation of antibodies to thymus-dependent antigen, and development of delayed-type hypersensitivity. However, no complete recovery of the NSR parameters impaired by 2-chloroethenyldichloroarsine is observed.