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[Structural-metabolic characteristics of erythrocyte membrane in patients with paranoid schizophrenia undergoing psychopharmacotherapy].

作者信息

Novitskiĭ V V, Riazantseva N V

机构信息

Pathologic Physiology Department, Siberian State Medical University, Institute of Pharmacology, Tomsk Scientific Center, Siberian Division, Russian Academy of Medical Sciences, pr. Lenina 3, Tomsk, 634028 Russia.

出版信息

Eksp Klin Farmakol. 2002 Nov-Dec;65(6):19-22.

Abstract

Structural features of the hydrophobic compartment and external parts of the erythrocyte membrane, Na+ and K+ ATPase activity, intensity of the free-radical oxidation of lipids, and the surface relief of erythrocytes were studied in paranoic schizophrenia patients before and after a course of pharmacotherapy. It was established that the administration of neuroleptics in therapeutic doses does not cause damage of the erythrocyte membrane.

摘要

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