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感染滑膜支原体的鸡血清蛋白和类风湿因子的渐进性变化。

Progressive changes in serum proteins and the rheumatoid factor of chickens infected with Mycoplasma synoviae.

作者信息

Sells D M

出版信息

Avian Dis. 1976 Jan-Mar;20(1):108-17.

PMID:1259654
Abstract

Sera from controls and chickens infected with Mycoplasma synoviae were examined for serum protein content by cellulose-acetate electrophoresis, and for rheumatoid factor (RF) by a latex-agglutination test at 8, 18, 28, 38, and 48 days postinoculation (DPI). Mean total serum protein concentration was significantly elevated by 8 DPI and rose to much higher concentrations on each subsequent day of examination. The mean albumin concentration was significantly decreased by 8 DPI, and continued to decline to very low levels at 18 and 28 DPI, after which it began to rise and by 48 DPI did not significantly differ from the controls. The mean alpha-globulin concentrations were significantly elevated on all days of examination. The mean beta- and gamma-globulin concentrations were significantly elevated by 8 DPI and reached maximum levels at 18 DPI but remained elevated throughout the test. The percentage of chickens having RF titers increased on each successive examination day, but only 56% of the chickens had titers at 48 DPI.

摘要

在接种后第8、18、28、38和48天,通过醋酸纤维素电泳检测对照组和感染滑膜支原体的鸡的血清蛋白含量,并通过乳胶凝集试验检测类风湿因子(RF)。接种后8天,血清总蛋白平均浓度显著升高,且在随后每次检查日都升至更高浓度。接种后8天,白蛋白平均浓度显著降低,并在18天和28天时持续降至极低水平,之后开始上升,到48天时与对照组无显著差异。在所有检查日,α-球蛋白平均浓度均显著升高。β-球蛋白和γ-球蛋白平均浓度在接种后8天显著升高,在18天时达到最高水平,但在整个试验过程中一直保持升高。在连续的每个检查日,RF滴度呈阳性的鸡的百分比都在增加,但在48天时,只有56%的鸡有滴度。

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