Hamm U, Chandrashekaran M K, Engelmann W
Z Naturforsch C Biosci. 1975 Mar-Apr;30(2):240-4. doi: 10.1515/znc-1975-3-416.
The phase shifting action of low temperature pulses of 6 degrees C and 2 h duration administered to the various phases of the Drosophila pseudoobscura circadian rhythm and the action of light pulses given 30 min after the beginning of these low temperature pulses have been investigated. The phase response curve obtained from experiments with light pulses during low temperature cannot be explained on the basis of a straightforward and sequential phase shifting of the oscillation by the various transitions in the pulses. The response curve, after the slight phase shifting action of the temperature pulses is corrected for, resembles the standard phase response curve4 for light pulses (at 20 degrees C) in its wave form but not in its time course. Our curve is shifted in time in a manner that indicates that the light pulses accompanying the low temperature pulses arrived at phase points 1.5 h later than the actual phases at which they were given. We attribute this delay to a slowing down of the information that is apparently transmitted by a process that is temperature dependent.
研究了持续2小时、温度为6摄氏度的低温脉冲施用于果蝇伪暗生物钟节律各阶段的相移作用，以及在这些低温脉冲开始30分钟后给予光脉冲的作用。在低温期间用光脉冲实验得到的相位响应曲线，无法基于脉冲中各种转变对振荡进行直接和连续的相移来解释。在对温度脉冲的轻微相移作用进行校正后，响应曲线在波形上类似于光脉冲（在20摄氏度时）的标准相位响应曲线4，但在时间进程上不同。我们的曲线在时间上的偏移方式表明，伴随低温脉冲的光脉冲到达的相位点比给予它们时的实际相位晚1.5小时。我们将这种延迟归因于信息传递的减慢，这显然是由一个与温度相关的过程导致的。
