Doroudchi M, Dehaghani A S, Emad K, Ghaderi A A
Department of Immunology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
East Mediterr Health J. 2001 Jan-Mar;7(1-2):128-38.
We used indirect ELISA assay to test 1193 sera for rubella IgG and IgM antibodies in a seroepidemiological survey of three age- and gender-differentiated sample populations in Shiraz: 203 children aged 2-7 years, 255 paired mothers and neonates (cord blood) and 480 women aged 14-70 years. Seropositivity among women aged 14-70 years was 96.2%. No IgM positive case was found among the 255 tested cord blood samples. Seropositivity among the 203 children was 97.0% (much higher than previously reported). This may be due to rubella epidemics, which tend to occur every 6-10 years. The impact of introducing rubella vaccination is discussed.
在设拉子进行的一项血清流行病学调查中，我们使用间接ELISA法检测了1193份血清中的风疹IgG和IgM抗体，该调查涉及三个按年龄和性别区分的样本群体：203名2至7岁的儿童、255对母婴（脐带血）以及480名14至70岁的女性。14至70岁女性的血清阳性率为96.2%。在255份检测的脐带血样本中未发现IgM阳性病例。203名儿童的血清阳性率为97.0%（远高于先前报道）。这可能是由于风疹流行往往每6至10年发生一次。文中讨论了引入风疹疫苗接种的影响。
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