Mrázová M, Smelhausová M, Sestáková Z, Svandová E, Benes C
Centre of Epidemiology and Microbiology, NRL for mumps, measles and rubella, National Institute of Public Health, Prague, Czech Republic.
Cent Eur J Public Health. 2003 Dec;11 Suppl:S42-9.
In total, 3,009 sera from a representative population sample of the Czech Republic, 1508 females and 1,501 males, were tested by EIA using a commercial kit ETI-RUBEK-G Plus manufactured by Dia Sorin, Italy. The vaccination strategy was as follows: vaccination of 12-year-old girls since 1982 and all 2-year-olds vaccinated since 1986. Currently, all women under 31 years of age and all men under 17 years of age have been vaccinated. The results of the serological survey confirmed lower seropositivity rates in young men compared to vaccinated women of the same age as expected. An epidemic outbreak of rubeola among young men is another evidence of that The seropositivity rate of 2- 9-year-old vaccinee children reaches almost 95%. The long-term morbidity trend in the Czech Republic is downward sloping, with a marked differentiation between the male and female populations.
总共对来自捷克共和国具有代表性人群样本的3009份血清进行了检测，其中女性1508人，男性1501人，采用意大利Dia Sorin公司生产的商用试剂盒ETI-RUBEK-G Plus通过酶免疫分析（EIA）进行检测。疫苗接种策略如下：自1982年起对12岁女孩进行疫苗接种，自1986年起对所有2岁儿童进行疫苗接种。目前，所有31岁以下女性和所有17岁以下男性均已接种疫苗。血清学调查结果证实，与预期的同龄接种疫苗女性相比，年轻男性的血清阳性率较低。年轻男性中麻疹的疫情爆发就是另一个证据。2至9岁接种疫苗儿童的血清阳性率几乎达到95%。捷克共和国的长期发病率呈下降趋势，男性和女性人群之间存在明显差异。
