Wagener Silke, Rayatt Sukh S, Tatman Andy J, Gornall Peter, Slator Rona
Birmingham Children's Hospital, Birmingham, England.
Cleft Palate Craniofac J. 2003 Mar;40(2):180-5. doi: 10.1597/1545-1569_2003_040_0180_moiwpr_2.0.co_2.
Several methods of treating babies with Pierre Robin sequence have been described since the condition itself was first documented in 1923. The main aim of treatment has been to relieve upper airway obstruction. Treatment methods used range from positioning of the baby to invasive surgery. The aim of this article was to describe the assessment, treatment, and monitoring methods used for babies referred with Pierre Robin sequence (PRS).
SETTING/PATIENTS: From December 1995 to May 2000, 22 consecutive patients were admitted to Birmingham Children's Hospital with PRS. Their airway and nutritional status were assessed and continuously monitored.
Treatment concentrated on the relief of airway obstruction with a nasopharyngeal airway (NPA) and nutritional support of the babies until they grew out of their respiratory and feeding difficulties.
Outcome measures were oxygen saturation, growth of the babies, and the need for surgery.
All babies were managed successfully with an NPA and nutritional support. No baby required surgery, and the majority showed good weight gain.
Relieving airway obstruction by NPA is an effective and safe treatment for babies with PRS until they have grown out of their respiratory and feeding difficulties. It avoids the need for surgery and can be used on neonatal wards using the monitoring described.
自1923年首次记录皮埃尔·罗宾序列征以来，已经描述了几种治疗患有该病症婴儿的方法。治疗的主要目的是缓解上呼吸道阻塞。所使用的治疗方法从婴儿的体位调整到侵入性手术不等。本文的目的是描述用于转诊患有皮埃尔·罗宾序列征（PRS）婴儿的评估、治疗和监测方法。
背景/患者：1995年12月至2000年5月，连续22例患有PRS的患者入住伯明翰儿童医院。对他们的气道和营养状况进行了评估并持续监测。
治疗集中于通过鼻咽气道（NPA）缓解气道阻塞以及对婴儿进行营养支持，直到他们克服呼吸和喂养困难。
结局指标为血氧饱和度、婴儿生长情况以及手术需求。
所有婴儿通过NPA和营养支持均成功得到治疗。没有婴儿需要手术，并且大多数婴儿体重增加良好。
对于患有PRS的婴儿，在他们克服呼吸和喂养困难之前，通过NPA缓解气道阻塞是一种有效且安全的治疗方法。它避免了手术的需要，并且可以在新生儿病房使用所描述的监测方法。
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