Crowell Timothy A, Kieffer Kevin M, Siders Craig A, Vanderploeg Rodney D
Department of Psychiatry and Behavioral Medicine, University of South Florida, Tampa, FL 33613, USA.
Clin Neuropsychol. 2002 Aug;16(3):310-21. doi: 10.1076/clin.16.3.310.13851.
Previous research investigating whether combat-related Posttraumatic Stress Disorder (PTSD) is associated with impaired neuropsychological functioning has yielded inconsistent findings. The present study addressed many methodological limitations of previous research. Neuropsychological measures of intellectual ability, learning, memory, attention, visuospatial ability, executive functioning, language, and psychomotor speed were compared in four groups of early middle-aged community dwelling veterans. The four demographically comparable groups were: (a) those with current PTSD symptoms (n=80); (b) those with a prior history of PTSD but not currently experiencing active PTSD symptoms (n=80); (c) a non-PTSD psychiatrically matched control group (n=80); and (d) a normal control group (n=80). Results indicated that the four groups did not statistically differ on the neuropsychological measures and that veterans with PTSD perform similarly to demographically matched controls. Results further suggested that the cognitive difficulties previously linked to PTSD may actually have been secondary to preexisting individual differences or other clinical conditions coexisting with PTSD.
先前关于与战斗相关的创伤后应激障碍(PTSD)是否与神经心理功能受损相关的研究结果并不一致。本研究解决了先前研究中的许多方法学局限性。对四组居住在社区的中年早期退伍军人进行了智力、学习、记忆、注意力、视觉空间能力、执行功能、语言和心理运动速度的神经心理学测量比较。这四个人口统计学特征相当的组分别是:(a)有当前PTSD症状的人(n = 80);(b)有PTSD既往史但目前未出现活动性PTSD症状的人(n = 80);(c)一个非PTSD的精神疾病匹配对照组(n = 80);以及(d)一个正常对照组(n = 80)。结果表明,这四组在神经心理学测量上没有统计学差异,患有PTSD的退伍军人的表现与人口统计学特征匹配的对照组相似。结果进一步表明,先前与PTSD相关的认知困难实际上可能是个体差异或与PTSD共存的其他临床状况所致。