Gilbertson M W, Gurvits T V, Lasko N B, Orr S P, Pitman R K
Manchester Veteran's Administration Medical Center, Manchester, New Hampshire, USA.
J Trauma Stress. 2001 Apr;14(2):413-32. doi: 10.1023/A:1011181305501.
Declarative memory impairment is a frequent complaint of patients suffering from posttraumatic stress disorder (PTSD). We assessed memory, attention, visual spatial skills, and executive function in Vietnam combat veterans with (n = 19) and without (n = 13) PTSD. Although PTSD subjects demonstrated a "generalized impairment" relative to non-PTSD subjects on a majority of tasks, only attention and memory provided unique and independent prediction of PTSD versus non-PTSD status. Our findings suggest that memory functioning represents a neurocognitive domain of specific relevance to the development of PTSD in trauma-exposed individuals, which can be distinguished from generalized attentional impairment as well as the effects of trauma exposure severity, IQ, comorbid depression, history of alcohol use, and history of developmental learning problems.
陈述性记忆障碍是创伤后应激障碍（PTSD）患者常见的主诉。我们评估了患有（n = 19）和未患有（n = 13）PTSD的越南退伍军人的记忆、注意力、视觉空间技能和执行功能。尽管与非PTSD受试者相比，PTSD受试者在大多数任务上表现出“广泛性损伤”，但只有注意力和记忆能够对PTSD与非PTSD状态进行独特且独立的预测。我们的研究结果表明，记忆功能是创伤暴露个体中与PTSD发展特别相关的神经认知领域，它可以与广泛性注意力损伤以及创伤暴露严重程度、智商、共病抑郁、饮酒史和发育性学习问题史的影响区分开来。
