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[纵隔甲状腺肿所致急性呼吸衰竭的外科治疗。临床经验与结果]

[Surgical treatment of acute respiratory failure caused by mediastinal goiter. Clinical experience and results].

作者信息

Carditello Antonio, Milone Antonino, Stilo Francesco, Mollo Francesco, Basile Maurizio

机构信息

Dipartimento di Discipline Chirurgiche Generali e Speciali Policlinico Universitario di Messina.

出版信息

Chir Ital. 2002 Nov-Dec;54(6):807-10.

Abstract

In the regions where goitre is endemic, onset of the disease with acute respiratory insufficiency caused by thyroid compression is an uncommon situation requiring a rapid diagnosis and urgent surgical treatment. From January 1997 to December 2000 we observed 81 patients with thyroid pathologies, (69 males and 12 females; mean age 64 years). We found colloid-cystic goitre in 39 cases, adenomatous goitre in 26, carcinoma in 12, Hürthle's cell tumours in 3 and inflammatory disease in 1. All patients underwent thyroidectomy. Nine patients (11%) presented acute respiratory insufficiency caused by thyroid compression, with various associated phonesis disorders; in these cases we performed emergency surgery with postoperative maintenance of tracheal intubation or tracheotomy or the possible positioning of a self-expanding tracheal stent. In these 9 patients there were 4 deaths (44%), 3 in the immediate postoperative period and one after 10 months. We also observed one hydropneumothorax. Functional recovery was achieved in the remaining 5 patients. The treatment of this clinical picture requires urgent tracheal intubation, before the use of diagnostic tools, and it is important to maintain it after the surgical procedure for as long as is necessary for the tracheal wall to be reconstituted. In the severest cases a temporary tracheotomy is needed or the positioning of a tracheal stent, which offers a valid and effective alternative.

摘要

在甲状腺肿流行地区,因甲状腺压迫导致急性呼吸功能不全而发病的情况并不常见,需要快速诊断和紧急手术治疗。1997年1月至2000年12月,我们观察了81例甲状腺疾病患者(69例男性,12例女性;平均年龄64岁)。我们发现39例为胶样囊肿性甲状腺肿,26例为腺瘤性甲状腺肿,12例为癌,3例为许特耳氏细胞瘤,1例为炎症性疾病。所有患者均接受了甲状腺切除术。9例患者(11%)出现因甲状腺压迫导致的急性呼吸功能不全,并伴有各种相关的语音障碍;在这些病例中,我们进行了急诊手术,并在术后维持气管插管、气管切开或可能放置自膨式气管支架。在这9例患者中有4例死亡(44%),3例在术后即刻死亡,1例在10个月后死亡。我们还观察到1例血气胸。其余5例患者实现了功能恢复。对于这种临床情况的治疗,在使用诊断工具之前需要紧急气管插管,并且在手术后根据气管壁重建所需的时间尽可能长时间地维持气管插管很重要。在最严重的情况下,需要进行临时气管切开或放置气管支架,这是一种有效且可行的替代方法。

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