纽约市年轻注射吸毒者中人类免疫缺陷病毒、乙型肝炎病毒和丙型肝炎病毒感染发生率的差异

Variability in the incidence of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infection among young injecting drug users in New York City.

作者信息

Des Jarlais Don C, Diaz Theresa, Perlis Theresa, Vlahov David, Maslow Carey, Latka Mary, Rockwell Russell, Edwards Vincent, Friedman Samuel R, Monterroso Edgar, Williams Ian, Garfein Richard S

机构信息

Baron Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York, NY 10003, USA.

出版信息

Am J Epidemiol. 2003 Mar 1;157(5):467-71. doi: 10.1093/aje/kwf222.

DOI:10.1093/aje/kwf222

PMID:12615611

Abstract

Cohort studies of young (aged 18-30 years) injecting drug users recruited in 1997-1999 in the Harlem and Lower East Side areas of New York City, New York, were used to assess the incidence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). The authors found that HIV incidence was low at both sites: 0.8/100 person-years at the Harlem site and 0/100 person-years at the Lower East Side site. In contrast, HBV incidence was moderate (12.2/100 person-years) at the Harlem site and high (30.7/100 person-years) at the Lower East Side site. Similarly, HCV incidence was moderate (9.3/100 person-years) at the Harlem site and high (34.0/100 person-years) at the Lower East Side site. Results show that high rates of HBV and HCV transmission do not imply high rates of HIV transmission, even within an area of high HIV seroprevalence.

摘要

对1997年至1999年在纽约市哈莱姆区和下东区招募的年轻（18 - 30岁）注射吸毒者进行队列研究，以评估人类免疫缺陷病毒（HIV）、乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）的发病率。作者发现，两个地点的HIV发病率都很低：哈莱姆区为0.8/100人年，下东区为0/100人年。相比之下，哈莱姆区的HBV发病率中等（12.2/100人年），而下东区则较高（30.7/100人年）。同样，哈莱姆区的HCV发病率中等（9.3/100人年），下东区则较高（34.0/100人年）。结果表明，即使在HIV血清阳性率较高的地区，HBV和HCV的高传播率并不意味着HIV的高传播率。