Mahmood Asif, Salaman Robert, Sintler Martin, Smith Simon R G, Simms Malcolm H, Vohra Rajiv K
Department of Vascular Surgery, University Hospital, Birmingham NHS Trust, Selly Oak Hospital, Birmingham B29 6JD, England, UK.
J Vasc Surg. 2003 Mar;37(3):586-93. doi: 10.1067/mva.2003.141.
Management of asymptomatic popliteal aneurysm is controversial, and the prognosis for acutely thrombosed aneurysm is notoriously poor. We evaluated the management and outcome for popliteal aneurysm.
A retrospective review of all patients with popliteal aneurysm between 1988 and 2000 was carried out. Fifty-two limbs were operated on in 41 patients. Data collected included findings at presentation, operative details, graft patency, limb salvage, complications, and 30-day mortality.
Initial findings included acute ischemia (n = 14), no symptoms (n = 29), acute rupture (n = 2), chronic ischemia (n = 5), and symptoms of nerve or vein compressive (n = 2). All patients with symptomatic aneurysms and 22 patients with asymptomatic aneurysms (21 larger than 2 cm in diameter, 1 with thrombus at duplex ultrasound scanning) underwent surgery as first-line treatment. Of the 7 patients with asymptomatic aneurysm managed with surveillance with duplex ultrasound scanning, acute ischemia developed in three, 1 aneurysm ruptured, compressive symptoms developed in 1, and 2 remained asymptomatic but required surgery because of aneurysm enlargement (>2 cm). Of the 17 patients with acute ischemia, 13 had neurologic signs and underwent immediate thromboembolectomy (trifurcation alone in 8, ankle-level arteriotomy in 4) and bypass grafting (n = 12) or inlay grafting (n = 1), and the other 4 underwent intra-arterial thrombolysis initially. Of these 4 procedures, 2 were successful and had elective surgery; the other 2 required urgent surgery because of secondary distal embolism and failure of recanalization. Thirteen of the 17 grafts were to the crural vessels. Bypass grafting (medial approach) was used in 16 of the 17 patients with acute ischemia, all 5 patients with chronic ischemia, and the 8 patients with no symptoms. An inlay technique (posterior approach) was used in 16 patients with no symptoms, the 3 patients with symptoms of nerve or vein compression, and 1 patient with acute ischemia. The distal anastomoses were to the below-knee popliteal artery in 35 patients and the crural arteries in 15 patients, using autologous vein. Two of the patients with rupture underwent ligation alone, the other undergoing bypass grafting in addition. The overall 5-year primary patency rate was 69%, secondary patency rate was 87%, and limb salvage rate was 87%. Limb salvage was achieved in 14 of the 17 patients with acute ischemia. Patients with asymptomatic aneurysms had better secondary graft patency (100%) compared with symptomatic aneurysms (74%; P <.01). Acute ischemia, technique used, and crural artery grafts were not predictors of graft failure with either univariate or multivariate analysis. Symptomatic aneurysms were associated with more postoperative complications and greater 30-day mortality (4 of 28 vs 0 of 24).
Thromboembolectomy followed by crural bypass grafting is an effective treatment for popliteal aneurysm with severe acute limb ischemia. Outcome is better with surgical management of asymptomatic popliteal aneurysm compared with symptomatic aneurysm.
无症状腘动脉瘤的治疗存在争议,急性血栓形成的动脉瘤预后极差。我们评估了腘动脉瘤的治疗方法及结果。
对1988年至2000年间所有腘动脉瘤患者进行回顾性研究。41例患者的52条肢体接受了手术。收集的数据包括就诊时的检查结果、手术细节、移植物通畅情况、肢体挽救情况、并发症及30天死亡率。
初始检查结果包括急性缺血(n = 14)、无症状(n = 29)、急性破裂(n = 2)、慢性缺血(n = 5)以及神经或静脉受压症状(n = 2)。所有有症状的动脉瘤患者及22例无症状动脉瘤患者(21例直径大于2 cm,1例经双功超声扫描发现有血栓)接受手术作为一线治疗。在7例采用双功超声扫描监测的无症状动脉瘤患者中,3例发生急性缺血,1例动脉瘤破裂,1例出现受压症状,2例无症状但因动脉瘤增大(>2 cm)而需要手术。在17例急性缺血患者中,13例有神经体征,接受了即刻血栓切除术(8例仅行三叉分支切开,4例在踝关节水平行动脉切开)及旁路移植术(n = 12)或嵌入移植术(n = 1),另外4例最初接受动脉内溶栓治疗。在这4例手术中,2例成功并接受了择期手术;另外2例因继发远端栓塞和再通失败而需要紧急手术。17例移植物中有13例是移植到小腿血管。17例急性缺血患者中的16例、所有5例慢性缺血患者及8例无症状患者采用旁路移植术(内侧入路)。16例无症状患者、3例有神经或静脉受压症状的患者及1例急性缺血患者采用嵌入技术(后侧入路)。35例患者的远端吻合口位于膝下腘动脉,15例患者的远端吻合口位于小腿动脉,均使用自体静脉。2例破裂患者仅接受结扎,另1例还接受了旁路移植术。总体5年一期通畅率为69%,二期通畅率为87%,肢体挽救率为87%。17例急性缺血患者中有14例实现了肢体挽救。无症状动脉瘤患者的移植物二期通畅率(100%)高于有症状动脉瘤患者(74%;P <.01)。单因素或多因素分析显示,急性缺血、所用技术及小腿动脉移植物均不是移植物失败的预测因素。有症状的动脉瘤与更多术后并发症及更高的30天死亡率相关(28例中有4例,而24例无症状患者中无死亡)。
血栓切除术联合小腿旁路移植术是治疗伴有严重急性肢体缺血的腘动脉瘤的有效方法。与有症状的动脉瘤相比,无症状腘动脉瘤的手术治疗效果更好。