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年龄和手术类型会影响腹腔镜结肠切除术患者的选择。

Age and type of procedure influence the choice of patients for laparoscopic colectomy.

作者信息

Sklow B, Read T, Birnbaum E, Fry R, Fleshman J

机构信息

Division of Colon and Rectal Surgery, Department of Surgery, University of Cincinnati, 231 Albert Sabin Way, Post Office Box 670558, Cincinnati, OH 45267-0558, USA.

出版信息

Surg Endosc. 2003 Jun;17(6):923-9. doi: 10.1007/s00464-002-8949-9. Epub 2003 Mar 7.

Abstract

BACKGROUND

The aim of this retrospective, case-matched controlled study was to determine the benefit of laparoscopic-assisted colectomy (LC) for the elderly (>75 years of age) and the young (<75 years of age) compared to an open colectomy (OC) control group.

METHODS

A retrospective review of 39 patients older than 75 years of age and 38 patients younger than 75 years of age who underwent LC for colorectal cancer between 1991 and 1999 was performed. LC patients were matched with an open control group for procedure, age, gender, year of procedure, and surgeon. Procedures included right and left colectomy, anterior resection of the rectosigmoid, and abdominoperineal resection. Measured intraoperative variables included anesthesia time, operative time, and estimated blood loss. Postoperative parameters consisted of duration of intravenous or epidural narcotic usage, return of bowel function (RBF), length of stay, and independence at discharge. These variables were compared in the entire group of 154 patients.

RESULTS

Mean ages were 81.4 and 81.8 years for LC and OC age >75 and 62.9 and 62.7 for LC and OC age <75. Mean anesthesia time and operative time were significantly longer (p < 0.05) for LC compared to OC (46.8 vs 39.3 and 159.3 vs 111.7 min, respectively) for age >75 and for age <75 (47.1 vs 40.3 and 182.8 vs 135.5 min, respectively). LC achieved faster recovery in both age groups: RBF (3.9 vs 4.9 days for age >75; 6.7 vs 7.7 days for age <75) (p < 0.05). Narcotic usage was shorter for the LC group age <75 (3.3 vs 4.4 days; p < 0.05). There was no significant difference in independence at discharge between LC and OC in either age group. Faster recovery was seen with left LC in age >75 and right LC in age <75 compared to OC.

CONCLUSION

The advantages of LC over OC are the same for the elderly and the young. There may be a selective benefit of laparoscopic left colectomy in the elderly and laparoscopic right colectomy in the young.

摘要

背景

这项回顾性病例对照研究的目的是确定与开放结肠切除术(OC)对照组相比,腹腔镜辅助结肠切除术(LC)对老年患者(>75岁)和年轻患者(<75岁)的益处。

方法

对1991年至1999年间接受LC治疗结直肠癌的39例75岁以上患者和38例75岁以下患者进行回顾性分析。将LC患者与开放手术对照组在手术方式、年龄、性别、手术年份和手术医生方面进行匹配。手术包括右半结肠切除术、左半结肠切除术、直肠乙状结肠前切除术和腹会阴联合切除术。术中测量的变量包括麻醉时间、手术时间和估计失血量。术后参数包括静脉或硬膜外麻醉使用时间、肠功能恢复(RBF)、住院时间和出院时的自理能力。在这154例患者的整个队列中对这些变量进行比较。

结果

年龄>75岁的LC组和OC组平均年龄分别为81.4岁和81.8岁,年龄<75岁的LC组和OC组平均年龄分别为62.9岁和62.7岁。与OC组相比,年龄>75岁时LC组的平均麻醉时间和手术时间显著更长(p<0.05)(分别为46.8分钟对39.3分钟和159.3分钟对111.7分钟),年龄<75岁时也是如此(分别为47.1分钟对40.3分钟和182.8分钟对135.5分钟)。两个年龄组中LC组均实现了更快的恢复:RBF(年龄>75岁时为3.9天对4.9天;年龄<75岁时为6.7天对7.7天)(p<0.05)。年龄<75岁的LC组麻醉使用时间更短(3.3天对4.4天;p<0.05)。两个年龄组中LC组和OC组出院时的自理能力均无显著差异。与OC组相比,年龄>75岁时左半结肠LC恢复更快,年龄<75岁时右半结肠LC恢复更快。

结论

LC相对于OC的优势在老年和年轻患者中是相同的。对于老年患者,腹腔镜左半结肠切除术可能有选择性益处,对于年轻患者,腹腔镜右半结肠切除术可能有选择性益处。

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