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儿科心脏病学的新进展有哪些。

What is new in pediatric cardiology.

作者信息

Gupta Monesha L, Lantin-Hermoso M Regina, Rao P Syamasundar

机构信息

Division of Pediatric Cardiology, Department of Pediatrics, University of Texas-Houston Medical School, Memorial Hermann Children's Hospital, Houston, Texas 77030, USA.

出版信息

Indian J Pediatr. 2003 Jan;70(1):41-9. doi: 10.1007/BF02722744.

Abstract

Enormous advances in the diagnosis and management of heart disease in pediatric patient have taken place during the last-four decades. In this review the authors will concentrate on the developments within the last five to ten years. It will deal with what may be called medical advances. Recent advances in molecular genetics and defining the familial patterns have led to finding that certain genetic and molecular factors are linked to congenital heart disease and arrythmia, thus providing opportunity for improved genetic counseling and future gene therapy. Medical treatment of congenital heart disease targets not only the augmentation of ventricular contractility (positive inotropy) but also addresses the neuro-humoral derangement associated with it. The ultrasound technology for the evaluation of the heart has come a long way from the early A-mode and M-mode capabilities to color Doppler, 2-dimentional and 3-dimentional capabilities.

摘要

在过去的四十年里,儿科患者心脏病的诊断和管理取得了巨大进展。在这篇综述中,作者将专注于过去五到十年内的发展。它将涉及所谓的医学进展。分子遗传学和确定家族模式的最新进展已导致发现某些遗传和分子因素与先天性心脏病和心律失常有关,从而为改善遗传咨询和未来的基因治疗提供了机会。先天性心脏病的医学治疗不仅针对增强心室收缩力(正性肌力作用),还解决与之相关的神经体液紊乱问题。用于评估心脏的超声技术已经从早期的A模式和M模式功能发展到彩色多普勒、二维和三维功能,取得了长足的进步。

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