Sutherland John E, Sutherland Steven J, Hoehns James D
Northeast Iowa Family Practice Residency Program, Waterloo 50702, USA.
J Fam Pract. 2003 Mar;52(3):201-9.
Combined treatment with psychotherapy or psychiatric consult and drug therapy has shown better response in several studies than either therapy alone. Although not proven by clinical trials, selecting a medication by matching its side-effect profile to patient characteristics is supported by case reports and likely enhances compliance. Patients who do not improve with initial therapy often benefit from being switched to another class of antidepressants, or having a drug from another class added to their therapy.
在多项研究中，心理治疗或精神科会诊与药物治疗相结合的联合治疗比单独使用任何一种治疗方法都显示出更好的疗效。尽管临床试验尚未证实，但病例报告支持根据药物副作用特征与患者特点相匹配来选择药物，这可能会提高依从性。初始治疗无效的患者通常会从换用另一类抗抑郁药或在治疗中添加另一类药物中获益。
