血栓形成过程中的CD62表达。

CD62 expression during thrombus formation.

作者信息

Saving Kay L, Mankin Peggy E

机构信息

Children's Hospital of Illinois, Department of Pediatrics, IL 61637, USA.

出版信息

J Pediatr Hematol Oncol. 2003 Mar;25(3):266-9. doi: 10.1097/00043426-200303000-00017.

DOI:10.1097/00043426-200303000-00017

PMID:12621250

Abstract

A large right atrial mass was discovered in a 16-year-old female patient receiving chemotherapy treatment for Hodgkin disease. The patient was participating in a platelet function research study. During laboratory examination of platelet activation, increasing CD62 and CD63 expression were found to mirror the clot formation. Further investigation of platelet expression of CD62 and CD63 by flow cytometry might reveal it to be a valuable tool in predicting impending thrombus formation.

摘要

在一名因霍奇金病接受化疗的16岁女性患者中发现了一个巨大的右心房肿块。该患者正在参与一项血小板功能研究。在血小板活化的实验室检查过程中，发现CD62和CD63表达的增加反映了血栓形成。通过流式细胞术进一步研究血小板CD62和CD63的表达可能会发现它是预测即将发生的血栓形成的一种有价值的工具。