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特应性和非特应性犬血清总免疫球蛋白E浓度的研究。

Studies of serum total immunoglobulin E concentrations in atopic and non-atopic dogs.

作者信息

Fraser M A, McNeil P E, Gettinby G

机构信息

Department of Veterinary Pathology, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH.

出版信息

Vet Rec. 2003 Feb 8;152(6):159-63. doi: 10.1136/vr.152.6.159.

DOI:10.1136/vr.152.6.159
PMID:12622285
Abstract

The serum total immunoglobulin E (IgE) concentrations of two groups of atopic dogs and three groups of non-atopic dogs were compared. There was a wide range of concentrations with a high degree of overlap between the groups. The serum total IgE concentrations of a group of 15 non-atopic racing greyhounds were significantly higher than those of all the other groups. Atopic and non-atopic dogs receiving stringent parasite control treatments could not be differentiated on the basis of their serum total IgE concentrations. In the non-atopic dogs there was no correlation between their serum total IgE concentrations and the number of allergen-specific positive results obtained in an ELISA, or between their serum total IgE concentrations and their age.

摘要

比较了两组特应性犬和三组非特应性犬的血清总免疫球蛋白E(IgE)浓度。两组之间的浓度范围很广且有高度重叠。一组15只非特应性赛犬的血清总IgE浓度显著高于所有其他组。接受严格寄生虫控制治疗的特应性和非特应性犬无法根据其血清总IgE浓度进行区分。在非特应性犬中,其血清总IgE浓度与ELISA中获得的过敏原特异性阳性结果数量之间,或其血清总IgE浓度与年龄之间均无相关性。

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