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睡眠呼吸障碍症状随种族和族裔的差异:睡眠心脏健康研究

Variation in symptoms of sleep-disordered breathing with race and ethnicity: the Sleep Heart Health Study.

作者信息

O'Connor George T, Lind Bonnie K, Lee Elisa T, Nieto F Javier, Redline Susan, Samet Jonathan M, Boland Lori L, Walsleben Joyce A, Foster Gregory L

机构信息

Department of Medicine, Boston University School of Medicine, Boston, MA 02118-2394, USA.

出版信息

Sleep. 2003 Feb 1;26(1):74-9.

Abstract

STUDY OBJECTIVES

To examine the relation of sleep-related symptoms to race and ethnicity in a diverse sample of middle-aged and older men and women.

DESIGN

Cross-sectional questionnaire survey.

SETTING

In the initial phase of the Sleep Heart Health Study, men and women enrolled in participating epidemiologic cohort studies were surveyed.

PARTICIPANTS

13,194 men and women 40 years of age and older, including 11,517 non-Hispanic white, 648 black, 643 American Indian, 296 Hispanic, and 90 Asian-Pacific Islander.

INTERVENTIONS

Not applicable.

MEASUREMENTS AND RESULTS

After adjustment for BMI and other factors, frequent snoring was more common among Hispanic women (odds ratio (OR) = 2.25, 95% confidence interval (CI) = 1.48, 3.42) and black women (OR = 1.55, 95% Ci = 1.13, 2.13) than among non-Hispanic white women. Hispanic men were significantly more likely to report frequent snoring than non-Hispanic white men (OR = 2.30, 95% CI = 1.43, 3.69). Black, American Indian, and Asian men did not differ significantly from white men in snoring prevalence. American Indian women were significantly more likely to report breathing pauses during sleep than their white, non-Hispanic counterparts (OR = 1.52, 95% CI 1.03, 2.24), although polysomnography data on a subset of the sample suggested that the association between this symptom reported on questionnaire and objective evidence of sleep-disordered breathing may be weaker among American Indians than among other groups. Mean Epworth Sleepiness Scale scores were slightly higher in black men and women than in their white, non-hispanic counterparts.

CONCLUSIONS

Frequent snoring was more common among black and Hispanic women and Hispanic men than among their white non-Hispanic counterparts, even after adjusting for BMI and other factors. Further research including polysomnography and objective measurements of sleepiness is needed to assess the physiologic and clinical significance of these findings.

摘要

研究目的

在一个包含中年及老年男性和女性的多样化样本中,研究与睡眠相关症状和种族及民族之间的关系。

设计

横断面问卷调查。

背景

在睡眠心脏健康研究的初始阶段,对参与流行病学队列研究的男性和女性进行了调查。

参与者

13194名年龄在40岁及以上的男性和女性,包括11517名非西班牙裔白人、648名黑人、643名美国印第安人、296名西班牙裔和90名亚太岛民。

干预措施

不适用。

测量与结果

在对体重指数(BMI)和其他因素进行调整后,西班牙裔女性(优势比(OR)=2.25,95%置信区间(CI)=1.48,3.42)和黑人女性(OR =1.55,95%CI =1.13,2.13)中频繁打鼾的情况比非西班牙裔白人女性更为常见。西班牙裔男性报告频繁打鼾的可能性显著高于非西班牙裔白人男性(OR =2.30,95%CI =1.43,3.69)。黑人、美国印第安人和亚洲男性在打鼾患病率上与白人男性没有显著差异。美国印第安女性在睡眠期间报告呼吸暂停的可能性显著高于非西班牙裔白人女性(OR =1.52,95%CI 1.03,2.24),尽管样本子集的多导睡眠图数据表明,美国印第安人中问卷报告的这种症状与睡眠呼吸紊乱的客观证据之间的关联可能比其他群体弱。黑人男性和女性的平均埃普沃思嗜睡量表得分略高于非西班牙裔白人。

结论

即使在对BMI和其他因素进行调整后,黑人及西班牙裔女性和西班牙裔男性中频繁打鼾的情况比非西班牙裔白人更为常见。需要进一步开展包括多导睡眠图和嗜睡客观测量在内的研究,以评估这些发现的生理和临床意义。

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