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威斯康星睡眠队列研究中的睡眠呼吸障碍与自我报告的总体健康状况

Sleep-disordered breathing and self-reported general health status in the Wisconsin Sleep Cohort Study.

作者信息

Finn L, Young T, Palta M, Fryback D G

机构信息

Department of Preventive Medicine, University of Wisconsin, Madison 53705, USA.

出版信息

Sleep. 1998 Nov 1;21(7):701-6.

PMID:11286346
Abstract

OBJECTIVE

To determine the relationship between sleep-disordered breathing and self-reported general health status. breathing status assessed by overnight in-laboratory polysomnography.

SETTING

General Community.

SUBJECTS

Employed men (n=421) and women (n=316), ages 30-60 years, enrolled in the Wisconsin Sleep Cohort Study.

INTERVENTIONS

None.

OUTCOME MEASURE

Self-reported general health profile and life satisfaction measured by the Medical Outcomes Survey Short Form-36 and obtained by interview.

RESULTS

Sleep-disordered breathing was associated with lower general health status before and after adjustment for age, sex, body mass index, smoking status, alcohol usage, and a history of cardiovascular conditions. Even mild sleep-disordered breathing (apnea-hypopnea index = 5) was associated with decrements in the Medical Outcomes Short Form 36 Survey health constructs comparable to the magnitude of decrements linked to other chronic conditions such as arthritis, angina, hypertension, diabetes, and back problems.

CONCLUSIONS

Sleep-disordered breathing is independently related to lower general health status, and this relationship is of clinical significance. Given the growing emphasis of the importance of patients' perceptions of health, these findings are relevant to estimating the overall impact of sleep-disordered breathing.

摘要

目的

确定睡眠呼吸紊乱与自我报告的总体健康状况之间的关系。通过夜间实验室多导睡眠图评估呼吸状况。

设置

普通社区。

研究对象

威斯康星睡眠队列研究中纳入的30至60岁的在职男性(n = 421)和女性(n = 316)。

干预措施

无。

观察指标

通过医学结局调查简表-36自我报告的总体健康状况和生活满意度,通过访谈获得。

结果

在对年龄、性别、体重指数、吸烟状况、饮酒情况和心血管疾病史进行调整前后,睡眠呼吸紊乱均与较低的总体健康状况相关。即使是轻度睡眠呼吸紊乱(呼吸暂停低通气指数 = 5)也与医学结局简表36调查健康指标的下降有关,其下降幅度与关节炎、心绞痛、高血压、糖尿病和背部问题等其他慢性疾病相关的下降幅度相当。

结论

睡眠呼吸紊乱与较低的总体健康状况独立相关,且这种关系具有临床意义。鉴于越来越强调患者对健康的认知的重要性,这些发现对于评估睡眠呼吸紊乱的总体影响具有重要意义。

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