Todisco Mauro, Casaccia Piergiorgio, Rossi Nazzareno
Local Health Department of National Health Service, Fermo, Italy.
Am J Ther. 2003 Mar-Apr;10(2):135-6. doi: 10.1097/00045391-200303000-00010.
The prognosis of patients with idiopathic thrombocytopenic purpura refractory to corticosteroids and splenectomy (refractory ITP) is poor; these patients present high morbidity from disease and its treatment and have a mortality rate of approximately 16%. A patient is reported with severe bleeding symptoms related to refractory ITP successfully treated with melatonin.
对皮质类固醇和脾切除术难治的特发性血小板减少性紫癜（难治性ITP）患者预后较差；这些患者因疾病及其治疗而具有较高的发病率，死亡率约为16%。本文报告了一名与难治性ITP相关的严重出血症状患者，用褪黑素成功治疗。
