Hommann M, Richter K K, Heyne J, Behrend U, Rimpler H, Will U, Bartel M, Scheele J
Klinik für Allgemeine und Viszerale Chirurgie, Friedrich-Schiller-Universität Jena.
Zentralbl Chir. 2003 Feb;128(2):155-8; discussion 159-60. doi: 10.1055/s-2003-37770.
For surgeons the acute intestinal ischaemia is still a diagnostic and therapeutic challenge. If clinically suspected, the diagnostic procedures such as duplex sonography and arterial angiography should be carried out immediately. Although the diagnosis is often quickly clear, perioperative mortality rate remains high. We report the acute local thrombolytic therapy as an alternative treatment.
A 80-year-old male patient was referred to our hospital with a complete occlusion of the superior mesenteric artery. Duplex sonography and the arterial angiogram confirmed the clinical diagnosis. Because the patient was assessed to be at high risk we decided to avoid an operation and local thrombolytic therapy using rt-PA and urokinase was carried out.
The local thrombolytic therapy was successful and led to a complete restoration of the arterial flow within the superior mesenteric artery. The clinical symptoms subsided and no complications were observed.
Local thrombolytic therapy appears to be a suitable therapeutic option in patients suffering of mesenteric arterial occlusion. Although the duplex sonography often confirms the diagnosis with high accuracy the angiography remains the diagnostic gold standard.
对于外科医生来说,急性肠缺血仍然是一个诊断和治疗上的挑战。如果临床上怀疑,应立即进行诸如双功超声检查和动脉血管造影等诊断程序。尽管诊断通常很快就能明确,但围手术期死亡率仍然很高。我们报告急性局部溶栓治疗作为一种替代治疗方法。
一名80岁男性患者因肠系膜上动脉完全闭塞被转诊至我院。双功超声检查和动脉血管造影证实了临床诊断。由于该患者被评估为高风险,我们决定避免手术,并使用rt-PA和尿激酶进行局部溶栓治疗。
局部溶栓治疗成功,导致肠系膜上动脉内动脉血流完全恢复。临床症状消退,未观察到并发症。
局部溶栓治疗似乎是肠系膜动脉闭塞患者的一种合适治疗选择。尽管双功超声检查通常能高度准确地确诊,但血管造影仍然是诊断的金标准。