Busby G, Ali Z, Simeon D T, Khan O, Abhang V
Neonatal Unit, Mt Hope Women's Hospital, Department of Clinical Medical Sciences, Department of Public Health and Community Medicine, and the Radiology Unit, University of the West Indies, St Augustine, Trinidad and Tobago, West Indies.
West Indian Med J. 2002 Dec;51(4):225-7.
This retrospective study examined the records of 44 mothers and 44 babies with a positive blood VDRL test and/or who showed symptoms of congenital syphilis at the Mount Hope Women's Hospital (MHWH), Trinidad, between June 1, 1996 and September 30, 1998. Long bone radiographs of 40/44 (91%) babies were assessed independently by two radiologists for signs of congenital syphilis and the data were analysed using frequency tables. Of the 44 mothers in the study, 34 (77%) were VDRL positive and the rest were either negative or unknown. Maternal age ranged from 14 to 39 years and most (92%) had antenatal care. Fourteen of the 34 (41%) VDRL positive mothers received treatment antenatally. All mothers were asymptomatic and none had any clinical features of syphilis. In 35/44 babies, the VDRL test was positive and in nine, the test was either negative or unknown. Twenty-six of the babies had signs suggestive of congenital syphilis and in 12, (46%) long bone radiographs revealed changes compatible with the diagnosis of congenital syphilis. Radiographic abnormalities were present only in infants with VDRL titres > 1:8.
这项回顾性研究调查了1996年6月1日至1998年9月30日期间在特立尼达霍普山妇女医院(MHWH)进行血液VDRL检测呈阳性和/或有先天性梅毒症状的44位母亲和44名婴儿的记录。44名婴儿中的40名(91%)的长骨X光片由两名放射科医生独立评估先天性梅毒迹象,并使用频率表对数据进行分析。在该研究的44位母亲中,34位(77%)VDRL呈阳性,其余母亲呈阴性或结果未知。母亲年龄在14至39岁之间,大多数(92%)接受过产前护理。34位VDRL呈阳性的母亲中有14位(41%)在产前接受过治疗。所有母亲均无症状,也没有任何梅毒的临床特征。44名婴儿中35名VDRL检测呈阳性,9名检测呈阴性或结果未知。26名婴儿有先天性梅毒的迹象,12名(46%)婴儿的长骨X光片显示有与先天性梅毒诊断相符的变化。X光片异常仅出现在VDRL滴度>1:8的婴儿中。