Piato José Roberto M, Barros Alfredo Carlos S D, Pincerato Kátia M, Sampaio Ana Paula Q, Pinotti José Aristodemo
Department of Obstetrics and Gynecology, University of São Paulo Medical School, Brazil.
Eur J Surg Oncol. 2003 Mar;29(2):118-20. doi: 10.1053/ejso.2002.1349.
Sentinel lymph node biopsy (SLN) seems to represent a reliable method for early breast cancer staging, offering an alternative to complete axillary dissection.
The identification of sentinel node(s), their localization and the predictive capacity of SLN were analysed in 42 patients who had neoadjuvant chemotherapy for breast cancer. Dextran labelled with (99m)Tc was injected close to the tumor. The radioactive uptake in the axilla was detected by scintigraphic images and by a hand-held probe guided the SLN.
One or more sentinel nodes were identified in 41 patients (97.6%). We could accurately predict axillary lymph nodes status in 93% of the cases.
SLN can predict the status of the axilla in patients who have received primary chemotherapy.
前哨淋巴结活检（SLN）似乎是早期乳腺癌分期的可靠方法，为全腋窝清扫提供了一种替代方案。
分析了42例接受乳腺癌新辅助化疗患者的前哨淋巴结识别、定位及其预测能力。将标记有（99m）Tc的葡聚糖注射到肿瘤附近。通过闪烁图像检测腋窝放射性摄取情况，并使用手持探头引导前哨淋巴结。
41例患者（97.6%）识别出一个或多个前哨淋巴结。93%的病例中我们能够准确预测腋窝淋巴结状态。
前哨淋巴结活检可预测接受过原发性化疗患者的腋窝状态。
