Schulz V, Schmidt W, Schanbel K H, Just H, Gladisch W
Klin Wochenschr. 1976 Apr 1;54(7):323-32. doi: 10.1007/BF01471578.
After myocardial infarction in the late period of recovery (13-25 months p. infarctum) pulmonary gas exchange in 23 patients was measured besides as hemodynamic parameters during exercise. The parameters take a course similar to that of subjects without lung and heart diseases. Arterial blood gas tensions (Pa02, Paco2) remain unchanged compared to resting values. Alveolar ventilation did show no difference in any of the patients. Minute ventilation VE, the various dead spaces, alveolar-arterial gas differences (AaDo2, aADco2) and ventilation-perfusion ratios of the whole lung VA/Q suggest however that these parameters show different courses according to the physical capacity of the patients. As the physical capacity of each patient is due to different cardiac functions taken by cardiac output and mixed venous blood gas tensions alterations of pulmonary gas exchange seemed to be dependent on the respective left ventricular function of the heart. Of the twenty-three patients, twelve with cardiac failure under exercise showed the most pronounced alterations in pulmonary gas exchange. Therefore, the different physical work capacity of the patients are determined only by cardiac function. No limitation of the productivity due to impeded lung function could be proved.
在心肌梗死后恢复期晚期(梗死后13 - 25个月),除了测量23例患者运动时的血流动力学参数外,还测量了肺气体交换情况。这些参数的变化过程与无肺部和心脏疾病的受试者相似。与静息值相比,动脉血气张力(Pa02、Paco2)保持不变。所有患者的肺泡通气均无差异。然而,分钟通气量VE、各种无效腔、肺泡 - 动脉血气差值(AaDo2、aADco2)以及全肺通气 - 灌注比VA/Q表明,这些参数根据患者的体能呈现不同的变化过程。由于每位患者的体能取决于心输出量和混合静脉血气张力所反映的不同心脏功能,肺气体交换的改变似乎取决于心脏各自的左心室功能。在这23例患者中,12例运动时出现心力衰竭的患者肺气体交换改变最为明显。因此,患者不同的体力工作能力仅由心脏功能决定。未证实存在因肺功能障碍导致的生产能力受限情况。