O'Connor Philip A, Eustace Stephen, O'Byrne John
National Spinal Injuries Unit, Department of Orthopaedic Surgery, Mater Misericordiae Hospital, Dublin, Ireland.
Spine (Phila Pa 1976). 2002 Sep 15;27(18):E413-5. doi: 10.1097/00007632-200209150-00024.
This report details the sudden catastrophic neurologic deterioration concerning a patient with an acute fracture of T5 associated with osteoporosis.
To describe a unique presentation of abrupt spinal cord injury in this condition.
Vertebral fractures occur frequently in osteoporosis, but associated spinal cord injury is a rare occurrence. When neurologic injury occurs it is generally of a very low incidence and with a gradual onset, and spontaneous recovery can be expected. Most reports in the literature are of delayed-onset paraplegia after vertebral collapse. We report a unique case of a sudden and catastrophic thoracic spinal cord injury occurring spontaneously.
An 88-year-old woman had a sudden thoracic vertebral fracture with complete spinal cord injury while attempting to get out of bed. She was treated with continuous oral corticosteroids for >40 years for both rheumatoid arthritis and restrictive lung disease. She was never investigated or treated for osteoporosis.
Plain radiographs indicated multilevel osteoporotic fractures throughout the spine with diffuse, marked osteopenia. Magnetic resonance imaging scans showed changes in keeping with severe vertebral osteoporosis and spinal cord injury. She was treated nonoperatively in view of the extremely osteoporotic spine and her overall poor medical condition. Despite an initial improvement in her respiratory condition with medical therapy, she died 72 hours following admission.
With increasing awareness of the morbidity attached to the osteoporotic spine, investigation and pharmacologic treatment are warranted and may reduce the possibility of catastrophic neurologic impairment as occurred in this case.
本报告详细描述了一名患有与骨质疏松症相关的T5急性骨折患者突然发生的灾难性神经功能恶化情况。
描述这种情况下急性脊髓损伤的独特表现。
椎体骨折在骨质疏松症中很常见,但相关的脊髓损伤却很少见。当发生神经损伤时,其发生率通常很低且起病缓慢,有望自发恢复。文献中的大多数报道是椎体塌陷后迟发性截瘫。我们报告了一例自发发生的突然且灾难性的胸段脊髓损伤的独特病例。
一名88岁女性在试图起床时突然发生胸椎骨折并伴有完全性脊髓损伤。她因类风湿性关节炎和限制性肺病接受持续口服皮质类固醇治疗超过40年。她从未接受过骨质疏松症的检查或治疗。
X线平片显示整个脊柱存在多节段骨质疏松性骨折,伴有弥漫性、明显的骨质减少。磁共振成像扫描显示与严重椎体骨质疏松和脊髓损伤相符的变化。鉴于脊柱骨质疏松极其严重且她的整体身体状况较差,对她进行了非手术治疗。尽管药物治疗使她的呼吸状况最初有所改善,但她在入院72小时后死亡。
随着对骨质疏松性脊柱所带来的发病率认识的提高,进行检查和药物治疗是必要的,这可能会降低像本例中发生的灾难性神经损伤的可能性。