Chen Chiu-Liang, Lee Cheng-Hung, Lee Tu-Sheng, Lin Yu-Min, Chen Yen-Jen
Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan.
J Formos Med Assoc. 2003 Jun;102(6):429-34.
Spinal epidural lipomatosis (SEL) frequently occurs as a result of long-term steroid administration for various disorders, and patients often present with osteoporosis. Acute paraplegia in patients with extensive thoracic SEL is rare. We report a case of acute paraplegia caused by osteoporotic compression fracture with extensive thoracic SEL in a 44-year-old man with rheumatoid arthritis who had received steroid therapy for 4 years. He presented initially with abdominal distension and weakness of lower limbs, and a sudden onset of paraplegia with complete motor and sensory loss below the T6 level ensued. Plain radiographs showed an osteoporotic compression fracture of the T6 vertebra. Magnetic resonance imaging showed osteoporotic compression fractures of the T5 and T6 vertebrae and SEL from T2 to T10 vertebrae. Decompressive laminectomy with epidural fat debulking was performed, and the pathology was confirmed as epidural lipomatosis. His neurological condition showed no improvement below the T6 level 3 months after surgery. Osteoporotic compression fracture is a risk factor for acute paraplegia in patients with thoracic SEL and decompressive surgery should be performed without delay.
脊髓硬膜外脂肪增多症(SEL)常因长期使用类固醇治疗各种疾病而发生,患者常伴有骨质疏松症。广泛胸段SEL患者出现急性截瘫的情况较为罕见。我们报告一例44岁类风湿关节炎男性患者,因骨质疏松性压缩骨折合并广泛胸段SEL导致急性截瘫,该患者已接受4年类固醇治疗。他最初表现为腹胀和下肢无力,随后突然发生截瘫,T6水平以下出现完全性运动和感觉丧失。X线平片显示T6椎体骨质疏松性压缩骨折。磁共振成像显示T5和T6椎体骨质疏松性压缩骨折以及T2至T10椎体的SEL。进行了减压椎板切除术并清除硬膜外脂肪,病理证实为硬膜外脂肪增多症。术后3个月,其T6水平以下神经功能无改善。骨质疏松性压缩骨折是胸段SEL患者急性截瘫的危险因素,应立即进行减压手术。