Cline Richard R, Mott David A
Department of Pharmaceutical Care and Health Systems, College of Pharmacy, University of Minnesota, 308 Harvard Street, S.E., Minneapolis, MN 55455, USA.
Am J Health Syst Pharm. 2003 Mar 1;60(5):453-63. doi: 10.1093/ajhp/60.5.453.
The factors contributing to the use of antiresorptive therapies (ARTs) and differentiating the ARTs used were examined. A list of names of community-dwelling persons 65 years or older living in Wisconsin was obtained, and 2100 individuals were selected (1050 men and 1050 women) to receive the 10-page survey instrument. The survey requested information on health status, prescription drug use, preferences for using prescription drugs versus self-treatment strategies, demographic characteristics, and status and type of prescription drug and medical insurance. Only the responses from female respondents were evaluated. Descriptive statistics were calculated for each variable. The simultaneous relationships among all variables were modeled sequentially using a binary logistic regression model and a multinomial logistic regression model. Usable responses were received from 629 women, yielding an adjusted response rate of 59.9%; 169 (26.9%) reported current use of at least one ART, 110 (17.5%) reported using hormone replacement therapy (HRT), and 59 (9.4%) were using newer ARTs. The typical respondent did not use any prescription medicines for the treatment or prevention of osteoporosis, was married, and did not have a four-year college degree. Married, younger women with high medical care preferences scores were more likely to use antiresorptive agents. Married women were more likely to use HRT versus no treatment. A higher number of family practice physicians per 100,000 population reduced the likelihood of the use of any ART. Lower age was also related to the use of ARTs. Marital status, age, medical care preferences, prescription drug insurance, a regular source of care, and the diagnosis of osteoporosis were all significantly associated with the use of any antiresorptive agent.
研究了促成抗吸收疗法（ARTs）使用以及区分所使用的ARTs的因素。获取了威斯康星州65岁及以上社区居住者的名单，并挑选了2100人（1050名男性和1050名女性）来接收这份10页的调查问卷。该调查询问了健康状况、处方药使用情况、使用处方药与自我治疗策略的偏好、人口统计学特征以及处方药和医疗保险的状况及类型。仅对女性受访者的回答进行了评估。对每个变量进行了描述性统计。使用二元逻辑回归模型和多项逻辑回归模型依次对所有变量之间的同步关系进行建模。收到了629名女性的可用回复，调整后的回复率为59.9%；169人（26.9%）报告目前至少使用一种ART，110人（17.5%）报告使用激素替代疗法（HRT），59人（9.4%）使用新型ART。典型的受访者未使用任何用于治疗或预防骨质疏松症的处方药，已婚，且没有四年制大学学位。医疗保健偏好得分高的已婚年轻女性更有可能使用抗吸收剂。已婚女性比不接受治疗的女性更有可能使用HRT。每10万人口中家庭医生数量较多会降低使用任何ART的可能性。年龄较小也与ART的使用有关。婚姻状况、年龄、医疗保健偏好、处方药保险、固定的医疗来源以及骨质疏松症的诊断均与任何抗吸收剂的使用显著相关。
