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丙硫氧嘧啶治疗后出现肝功能损害的甲亢合并妊娠患者使用卡比马唑成功治疗:一例病例报告

Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: a case report.

作者信息

Kontoleon P, Ilias I, Koutras D A, Kontogiannis D, Papapetrou P D

机构信息

Second Endocrine Department, Alexandra General Hospital, Athens, Greece.

出版信息

Clin Exp Obstet Gynecol. 2002;29(4):304-5.

Abstract

We report the case of a 27-year-old woman with hyperthyroidism during pregnancy. Antithyroid treatment with propylthiouracil (PTU) resulted in elevated hepatic enzymes and after the 12th week of pregnancy treatment was changed to carbimazole (CBZ). The remaining pregnancy, delivery and follow-up period were uneventful for the mother and her offspring. Antithyroid treatment during pregnancy should allow the use not only of PTU but also of CBZ and methimazole.

摘要

我们报告了一例27岁妊娠期甲状腺功能亢进症女性患者的病例。使用丙硫氧嘧啶(PTU)进行抗甲状腺治疗导致肝酶升高,妊娠12周后治疗改为卡比马唑(CBZ)。母亲及其后代在剩余的孕期、分娩期及随访期均平安无事。妊娠期抗甲状腺治疗不仅应允许使用PTU,还应允许使用CBZ和甲巯咪唑。

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